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Biomedical subjects

B A Stoll

Publications and source records attributed to B A Stoll.

At least 73 records · Page 4Linked to original sources

Rechallenging breast cancer with tamoxifen therapy.

Advanced breast cancer which has temporarily responded to a course of tamoxifen (Nolvadex) therapy may show a response a second or third time when rechallenged by the same agent subsequently. The interval between such treatments may be critical for response. The observation also has important implications in the management of recurrence in high risk patients who have received adjuvant therapy which includes tamoxifen, after their primary surgery.

Aged↗

Medical treatment of breast cancer.

Medical treatment is potentially more important than surgical treatment for the large majority of patients presenting withe breast cancer. Since each patient has unique characteristics affecting both tumour aggressiveness and host defence, a generalised approach to medical treatment is no longer acceptable.

Antineoplastic Agents↗

Thermographic changes following steroidal administration to patients with mammary cancer.

In 27 post-menopausal patients with soft-tissue lesions of advanced breast cancer, temperature changes in skin-over tumour have been evaluated for their ability to predict response to additive hormone therapy. The thermoprofile across the tumour and its bed was selected for measuring purposes in preference to other thermographic methods. Serial measurements were carried out before and during therapy, and the observations correlated with the clinical response to therapy. Of the 14 patients who showed decrease of at least 1 degree C in the thermoprofile peak value within 2 weeks of initiating hormonal therapy, 57% showed clinical evidence of tumour regression 3 months later. Of 13 patients who did not show this change, none showed tumour regression later.

Breast Neoplasms↗