PubMed Health⌕ Search

Biomedical subjects

B A WAALER

Publications and source records attributed to B A WAALER.

15 recordsLinked to original sources

Effect of dopamine on the isolated perfused lung lobes of the dog.

Dopamine (beta-3:4-dihydroxyphenylethylamine) has a pressor action on the pulmonary vascular bed in isolated perfused lung lobes of the dog. Its pulmonary vasoconstrictor effect in this preparation is about 1/20-1/30 that of adrenaline or noradrenaline. When compared with adrenaline, dopamine is less effective as a vasoconstrictor in the bronchial vascular system than in the pulmonary circulation. Even very large doses of dopamine had no bronchomotor effect in the isolated perfused lung lobes. Addition of dopamine alone, or of dopamine together with some "new" blood, sometimes caused a potentiation of the pulmonary vasoconstrictor responses to sympathetic nerve stimulation.

Animals↗

Angina pectoris.

Explore the source record for details and available documents.

Angina Pectoris↗