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Biomedical subjects

B A Wright

Publications and source records attributed to B A Wright.

At least 73 records · Page 4Linked to original sources

Round robin investigation of methods for the recovery of poliovirus from drinking water.

Six laboratories actively involved in water virology research participated in a methods evaluation study, conducted under the auspices of the American Society for Testing and Materials Committee on Viruses in the Aquatic Environment, Task Force on Drinking Water. Each participant was asked to examine the Viradel (virus adsorption-elution) method with cartridge-type Filterite filters for virus adsorption and organic flocculation and aluminum hydroxide-hydroextraction for reconcentration. Virus was adsorbed to filter media at pH 3.5 and eluted with either glycine buffer (pH 10.5) or beef extract-glycine (pHG 9.0). Considerable variation was noted in the quantity of virus recovered from four 100-liter samples of dechlorinated tapwater seeded with low (350 to 860 PFU) and high (1,837 to 4,689 PFU) doses of poliovirus type 1. To have a more uniform standard of comparison, all the test samples were reassayed in one laboratory, where titers were also determined for the virus seed. Test results of the Viradel-organic flocculation method indicated that the average percentage of virus recovery for low-input experiments was 66%, with a range of 8 to 20% in two laboratories, 49 to 63% in three laboratories, and 198% in one laboratory. For the high-input experiments, two laboratories reported recoveries of 6 to 12%, and four laboratories reported recoveries of 26 to 46%. For the Viradel aluminum hydroxide-hydroextraction procedure, two laboratories recovered 9 to 11%, whereas four obtained 17 to 34% for low-input experiments. For the high-input tests, two laboratories reported a recovery of 3 to 5%, and four recovered 11 to 18% of the seeded virus.(ABSTRACT TRUNCATED AT 250 WORDS)

Aluminum Hydroxide↗

Processing and transport of environmental virus samples.

Poliovirus-seeded tap water, conditioned with MgCl2 and passed through virus-adsorbing filters, gave better poliovirus recovery than water identically treated but conditioned with AlCl3. Elution of several filter types with beef extract yielded higher recoveries than did elution with glycine. Seeded samples filtered through various filters and stored showed considerable virus loss in 2 days when stored at 4 degrees C, whereas those stored at -70 degrees C gave stable virus recovery up to 4 days. Additionally, the use of antifoam during the elution process reduced foaming and increased virus recovery by 28%.

Microbiological Techniques↗

[Adenomatoid odontogenic tumor].

A case of odontogenic adenomatoid tumor is presented in which it is stressed that conservative surgical enucleation of the lesion is the treatment of choice. The clinical, radiographic and histopathologic features of this tumor are discussed. Close attention and supervision of the developing dentition allows early diagnosis and treatment thus avoiding the needless sacrifice of adjacent teeth and bone.

Adolescent↗

Odontogenic keratocysts presenting as periapical disease.

This article presents four examples of odontogenic keratocysts which appeared radiographically as periapical cysts. This unusual presentation of odontogenic keratocysts is discussed, and its significance for the clinician is reviewed. This article emphasizes the need for microscopic examination of all material surgically removed from the periapical region.

Adult↗

Candidiasis and atrophic tongue lesions.

In an attempt to shed more light on the role of Candida albicans in the genesis of median rhomboid glossitis, a three-part study of normal, atrophic, and cadaver tongues was undertaken. Occasional fungal hyphae were found in 36 percent of the clinically normal tongues. Hyphae were far more numerous in cytologic smears from atrophic tongue lesions than in those from normal tongues. More than 40 percent of the cadaver tongues showed fungal hyphae. The possible role of C. albicans as a cause of median rhomboid glossitis is discussed in the light of these findings.

Adolescent↗

Neural tumors of the oral cavity. A review of the spectrum of benign and malignant oral tumors of the oral cavity and jaws.

The clinical and histologic features of benign and malignant neural tumors of the oral cavity and jaws are reviewed. Some rarer histologic variants are mentioned. Particular attention is paid to the two syndromes involving neural tumors of the oral cavity, namely, neurofibromatosis and multiple endocrine neoplasia III. A previously unreported case of the latter is presented.

Amputation Stumps↗

The 29th Coulter Lecture. Person and situation: adjusting the rehabilitation focus.

Four factors are examined that deflect attention away from environmental considerations in accounting for a person's behavior. The factors are (a) proximity between person and behavior, (b) saliency of person as figure, environment as background, (c) covariation of behavior with person or situation, (d) position of the person as insider (actor) or outsider (observer). Theory, research and examples are brought to bear on the attribution analysis. Five recommendations are offered to check flawed human perception when engaging in a helping relationship.

Architectural Accessibility↗

Median rhomboid glossitis: not a misnomer. Review of the literature and histologic study of twenty-eight cases.

A series of twenty-eight cases of median rhomboid glossitis were studied histologically. Of these twenty-eight cases, 85 percent showed fungal hyphae in the parakeratin layer. The literature is reviewed, and additional evidence is presented to support the theory the median rhomboid glossitis is not a developmental condition but the clinical expression of a localized chronic fungal infection.

Adult↗

Behavioral thermoregulation in the squirrel monkey when response effort is varied.

Squirrel monkeys controlled the air temperature within their test chamber by pulling a chain to select between two preset air temperatures, 10 and 50 degrees C. When the force required to pull the chain was increased in steps from 2.94 to 6.86 N, interresponse interval increased, resulting in wider air temperature swings within the chamber. The average air temperature selected became progressively lower, producing a concomitant fall in skin temperature. However, internal body temperatures (rectal and brain stem) remained nearly constant due to a compensatory increase in metabolic heat production. By allowing a cooler, rather than warmer, environment to result from a decreased response rate, the monkeys guarded against hyperthermia, which they are ill equipped to handle autonomically.

Animals↗