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Biomedical subjects

B Añíbarro

Publications and source records attributed to B Añíbarro.

14 recordsLinked to original sources
PubMed2000

Allergy to eggs from duck and goose without sensitization to hen egg proteins.

BACKGROUND: Eggs are among the foods most frequently causing allergy. Hen eggs are the most important. Those of other birds are of lesser significance. OBJECTIVE: We report an unusual case of food allergy after consumption of eggs from duck and goose in an adult patient without hen egg allergy. METHODS: Skin prick tests were performed with fresh white and yolk from eggs of duck and goose and egg white, egg yolk, ovalbumin, and ovomucoid from hen egg. Specific serum IgE was measured to hen egg proteins. SDS-PAGE and IgE immunoblotting were carried out with egg white extracts from hen, duck, and goose. RESULTS: Skin tests were positive to egg whites from duck and goose. The skin tests and specific serum IgE were negative to hen egg proteins. Immunoblotting demonstrated the presence of specific IgE to a proteic band of molecular weight around 45 kd. CONCLUSIONS: We report a patient with an IgE-mediated allergy to egg white from duck and goose without hen egg allergy. Ovalbumin seems to be the responsible protein. The antigenic determinant of this protein seems to be specific of order Anseriforme and it is not present in the ovalbumin of order Galliforme.

Animals↗
PubMed1997

Immediate rhinoconjunctivitis induced by metamizole and metronidazole.

OBJECTIVE: To report a case of immediate rhinoconjunctivitis induced by both metamizole and metronidazole. METHODS: Skin-tests (prick and intradermal) were performed with metamizole, metronidazole, and espyramicine. Standard RAST was carried out with metamizole and metronidazole. Oral challenge tests were performed single blind with Rhodogil, metronidazole, espyramicine, metamizole, aspirin, and propyfenazone. RESULTS: Both skin tests and RAST were negative. We also found that the patient tolerated therapeutic doses of espyramicine, aspirin, and propyfenazone. Challenges with Rhodogil, metamizole, and metronidazole elicited immediate rhinoconjunctivitis. CONCLUSION: This is an exceptional case of immediate rhinoconjunctivitis induced by two unrelated drugs (metamizole and metronidazole). The pathogenic mechanism implicated in this process remains unclear. Inhibition of the cyclooxygenase pathway was excluded and we could not demonstrate the presence of specific IgE antibodies. Nevertheless, an immunologic or idiosyncratic mechanism could be responsible.

Adult↗
PubMed1997

Sulfadiazine-induced sialadenitis.

OBJECTIVE: To present a case of sialadenitis induced by sulfadiazine. CASE SUMMARY: A 50-year-old man with bronchitis developed swelling of the parotid glands and floor of the mouth as well as plugging in his ears 2 hours after ingestion of Bronco-aseptilex (sulfadiazine, cyclamate, and guaiacol). Skin-prick tests performed with serial dilutions of sulfadiazine and Bronco-aseptilex were all negative. We then performed oral challenge tests with Bronco-aseptilex, sulfadiazine, and other compounds of the commercial syrup. Enlargement of the salivary glands was observed after oral challenge tests with Bronco-aseptilex and sulfadiazine. CONCLUSIONS: We describe a patient who developed drug-induced sialadenitis. The oral challenge test confirmed that sulfadiazine was the etiologic agent.

Anti-Infective Agents↗
PubMed1995

Nonspecific bronchial hyperresponsiveness and development of asthma in children with hay fever.

It has been suggested that patients with allergic rhinitis who present nonspecific bronchial hyperresponsiveness (BHR) are those most likely to develop asthma. Therefore, a study was conducted in children with rhinoconjunctivitis to ascertain whether BHR to methacholine might predict the development of asthma in these patients. Fifteen patients with hay fever and no previous symptoms of asthma were selected. All underwent clinical symptom tests and methacholine tests, during the pollen season in the 4 consecutive years following the start of the study. At the end of this period, 5 patients had developed asthma. It may thus be affirmed that, in this group, neither the presence nor the degree of previous BHR was useful for predicting which patients would later develop asthma.

Asthma↗
PubMed1992

Asthma with sulfite intolerance in children: a blocking study with cyanocobalamin.

Sulfites have been implicated as the cause of bronchospasm in some subjects with asthma. However, there is still no universally accepted explanation of the pathogenesis of these reactions. We have studied five children with asthma with metabisulfite intolerance confirmed by oral challenge testing. The challenge test with metabisulfite was repeated after premedication of all the patients with 1.5 mg of oral cyanocobalamin. In four of the five patients treated with cyanocobalamin, bronchospasm did not develop in the second metabisulfite challenge. The possible mechanisms are discussed.

Administration, Oral↗