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B Acea Nebril

Publications and source records attributed to B Acea Nebril.

At least 37 records · Page 2Linked to original sources

[Undifferentiated small cell carcinoma (oat-cell type) of the colon. Prognostic and therapeutic implications].

AIM: This report reviews the clinical and pathologic features of four patients with small-cell anaplastic carcinoma (SCAC) of the colon and describes in detail their histological and immunohistochemical characteristics. METHODS: Four patients with a SCAC of the colon diagnosed by conventional light microscopy, immunohistochemistry and ultrastructure were reviewed; clinical presentation, tumor location and spread, surgical procedure, adjuvant therapy and clinical outcome were recorded. RESULTS: There were two women and two man, with an average age of 55 (range, 40-66) years. Two tumors were located in the sigmoid and two in right colon. Cases 1, 3 and 4 were removed at laparotomy by segmental resection along with lymph nodes. All cases had liver metastases. Pathologic study identified out-cell subtype in all cases and two histopathologic patterns: pure SCAC (cases 2 and 4) and mixed exocrine-SCC differentiation (cases 1 and 3). Three patients were treated with cyclophosphamide, cisplatin and etoposide. Two patients (cases 2 and 4) died of widely metastatic disease; cases 1 and 3 had partial remission lasting 9 and 3 months, respectively. CONCLUSIONS: Due to extremely aggressive behavior of colon SCAC with early metastatic spread, CT scans of the chest-abdomen and radionuclide bone scan should be performed. In the presence of metastatic disease, multiagent chemotherapy with combined etoposide and cisplatin should be instituted.

Adult↗

[Heterotopic gastric mucosa in the ileum with perforated ulcer].

Heterotopic gastric mucosa (HGM) in the small bowel, other than in the Meckel's diverticulum or other congenitally anomalous bowel, is exceedingly rare. A patient with HGM of the small intestine with perforation of the ileum due to ulceration of the adjacent mucosa is presented. The authors remark the importance of the histological criteria to differentiate between true HGM from metaplastic changes, two entities with different behavior and prognostic implications.

Aged↗

[Acute abdomen in anticoagulated patients. Its assessment and the surgical indications].

Bleeding complications associated with anticoagulant drugs can development abdominal pain simulating acute surgical conditions of abdomen. We report six cases of intraabdominal spontaneous haemorrhage presenting as an acute abdomen in patients on anticoagulant therapy: two rectus sheath hematomas, a abdominal wall hematoma, a spontaneous hemoperitoneum, a retroperitoneal hematoma and an intramural hematoma of the small bowel. The article conclude that computed tomography examination provided useful information in this complications because can demonstrate the size and location of the mass and its relation to normal intra-abdominal structures. Finally, authors expose the surgical indications of the different bleeding syndromes in this patients.

Abdomen, Acute↗

[Gastric leiomyosarcoma. Considerations for non-radical surgery].

Leiomyosarcomas of the stomach are uncommon tumors and because their rarity there is a lack of understanding of the best approach to their surgical treatment. This is a retrospective review of eleven patients surgically treated with a non-radical method. The median age was 70 years (range, 44 to 83 years) and the most common initial symptoms were abdominal pain (36%), abdominal mass (27%) and weight loss (18%). The most common site of tumor involvement was the middle stomach (63%) and posterior wall (36%) with a median size of 18 cm (range, 8 to 30 cm). Operations included wedge resection of the stomach (55%), subtotal gastrectomy (36%) and biopsy (9%). Neither lymphadenectomy nor extended gastrectomy with en bloc excision were carried out. Follow-up was complete in all patients and the median duration of follow-up was 41 months (range, 8 to 72 months). The overall 5-years survival was 72% and only two patients died because of their tumor. Our results suggest that non-radical surgery in gastric leiomyosarcoma is an appropriate method in the surgical management of these patients.

Actuarial Analysis↗

[Carcinoma in situ of the gallbladder. The prognostic and therapeutic implications].

We have studied samples from gallbladders of five patients with carcinoma in situ over a 6-year period. Two were men and three women with du age ranging between 38 and 68 years (mean age 56). The microscopic criteria employed for the diagnosis of carcinoma in situ were pseudostratification of the epithelium, nuclear crowding, loss of cell polarity, atypical mitotic divisions and absence of stromal invasion. Cholecystectomy was carried in all patients due to cholelithiasis. Signs and symptoms were those related to the presence of stones and none of the patients was the presence of carcinoma suspected clinically. All patients are alive and symptom-free 14-84 months after surgery. Authors concluded that patients with carcinoma in situ of the gallbladder usually follows a good course after cholecystectomy.

Adult↗

[Ogilvie syndrome. Diagnostic and therapeutic attitude].

Ogilvie's syndrome (OS) is a clinical condiction with the symptoms, signs and radiological appearances of acute bowell obstruction but without any apparent mechanical cause. Diagnosis and treatment are often delayed and many patients are still inappropriately managed which in turn results in an increase in morbidity and mortality. We have reviewed our experience in eleven patients with OS in order to establish a system for their diagnostic and therapeutic management.

Adult↗

[Intramural hematoma of the ileum complicating anticoagulant therapy].

The development of abdominal pain in the patient receiving anticoagulant therapy is more likely to pose a diagnostic dilemma. A group of intra-abdominal bleeding syndromes, which are extremely rare in patients with normal haemostasis, have been described in patients on anticoagulant therapy. Theses syndromes are of particular interest to surgeons because they simulate acute surgical conditions of the abdomen. We herein report the preoperative diagnosis of a spontaneous intramural hematoma of the small bowel by computed tomography. The authors conclude that CT should be used early in the diagnostic evaluation of abdominal pain and of acute abdomen in patients receiving anticoagulant therapy. Indications for the operative management of these patients include active bleeding, pneumoperitoneum, failure to improve with conservative management within 72 hours, worsening of symptoms, and uncertain diagnosis.

Acenocoumarol↗

Solitary hamartomatous duodenal polyp; a different entity: report of a case and review of the literature.

Solitary hamartomatous duodenal polyps are a clinical entity considered until now to express an incomplete or initial form of Peutz-Jeghers syndrome (PJ syndrome). Following our experience of 1 case, we analyzed the clinical characteristics of the 12 previously reported cases of solitary hamartomatous duodenal polyps. In none of these cases did we find any documentation of mucocutaneous pigmentation, a family or personal history of intestinal polyps, or local neoplastic degeneration of the disease, and all cases presented during the fifth or sixth decade of life. Thus, we conclude that solitary hamartomatous duodenal polyps constitute a different entity to PJ syndrome, the most appropriate elective treatment for which is endoscopic electrosurgical polypectomy.

Adult↗

[Surgical indications in acute pseudo-obstruction of the colon (Ogilvie syndrome)].

Acute pseudo-obstruction of the colon (APC), popularly known as Ogilvie's syndrome, has been the subject of numerous medical communications in the past two decades. In this paper three patients with APC managed surgically are presented. In two patients cecal perforation developed; in the third patient a discharge cecostomy was carried out because of a caecal diameter of 16 cm. Indications for the operative management of these patients include pneumoperitoneum, development of peritonitis in the area of the cecum, continued cecal distention after 48-72 hours of therapy with or without colonoscopy, cecal diameter greater than 12 cm, respiratory failure and uncertain diagnosis.

Acute Disease↗

[Cecovesical fistula of inflammatory origin simulating neoplasm of the cecum].

We describe a case of a caecovesical fistula in a 60-year-old woman caused by an inflammatory tumour of a probably appendicular origin which mimicked cancer of the caecum. The patient, had a history of idiopathic peripheral polineuropathy and chronic constipation. Presented urinary tract infection and fecaluria, without symptoms of appendicitis. At operation, a solid mass including the caecum and the fundus of the bladder was found, and the appendix was not identified. In view of the neoplastic appearance and the impossibility of separating the caecum from the bladder, "en bloc" right hemicolectomy and partial cystectomy were performed. The pathologic study showed the inflammatory nature of the lesion.

Aged↗

[Importance of surgical staging in patients with cancer of the exocrine pancreas].

A retrospective analysis of 64 patients with adenocarcinoma of the exocrine pancreas was carried out to determine the impact of stage of the disease and surgical treatment on survival. Significant differences (p < 0.05) were observed in the survival rates of stage I (36%), stage II (12%), stage III (15%) and stage IV (0%). Patients with pancreatectomy had better prognosis (32%) than those with palliative procedures (11%) (p < 0.025). The presence of positive lymph nodes in patients with tumor resection didn't show significant differences on survival. Survivors showed a short prodome of symptoms (< 3 weeks) and a resected neoplasm (p < 0.025).

Adenocarcinoma↗

[An inflammatory aortic aneurysm ruptured into the retroperitoneum and an extensive communication of the aneurysm with the vena cava inferior].

Aortocaval fistula is a rare complication of abdominal aortic aneurysms that occurs with a frequency of 1% of operative cases or less. In this report we present a case of aortocaval fistula associated with ruptured and inflammatory aortic aneurysm that became apparent after evacuation of the thrombus. The inferior cava was ligated. We discuss the clinical syndrome and the management of patients with aortocaval fistula secondary to an abdominal aortic aneurysm and the results of surgical repair.

Aged↗