Biomedical subjects
Publications and source records attributed to B Agus.
We describe 2 cases of acute encephalopathy in patients with connective tissue disease caused by small doses of ibuprofen. In addition to aseptic meningitis, both patients had altered mental status and focal neurologic signs, ophthalmoplegia in one and hemiparesis in the other. The spectrum of neurologic manifestations of ibuprofen hypersensitivity is reviewed.
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A simplified technique for a therapeutic injection of the temporomandibular joint has been presented. We have emphasized diagnosis of the condition, as well as indications and contraindications. If the injection is used where indicated, the results are quite successful. Since this technique is inherently less demanding than those so far described, it may overcome the reluctance of dentists to inject the TMJ and thereby make certain cases more responsive to treatment.
Various theories regarding temporomandibular joint symptoms are reviewed. Two hundred and forty six patients suffering from head, neck, or facial pain, or masticatory dysfunction were studied. In 108 of these patients, the diagnosis of temporomandibular joint synovitis, lateral pterygoid muscle dysfunction, or tenomyositis of the masseter muscle was made. Examination procedures, diagnosis, frequency of occurrence, and initial treatment of these conditions are described.
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Pulmonary nocardiosis developed in three male patients with systemic lupus erythematosus (SLE), all of whom had been or were being treated with steroids and cytotoxic agents. These three cases comprise virtually the entire experience of our medical center with this infectious agent since 1971, and no cases of nocardiosis have been seen in a large group of treated and untreated female SLE patients. Unlike nine of ten previously reported cases, our patients each survived the infection with appropriate therapy, and subsequently either did well or died of other disease complications. The predisposition of nocardial infection for immunologically suppressed male subjects appears to hold true in SLE in spite of the strong predilection of this disease for women.
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A case of scleroderma with severe Raynaud's phenomenon and vasculitis is presented, in whom bilateral aseptic necrosis of the lunate bones developed. To my knowledge, this is the first such case in the literature.