PubMed Health⌕ Search

Biomedical subjects

B Antalek

Publications and source records attributed to B Antalek.

4 recordsLinked to original sources
PubMed1998

Multivariate Image Analysis of Magnetic Resonance Images with the Direct Exponential Curve Resolution Algorithm (DECRA).

Antalek and Windig recently presented a fast method to resolve a series of NMR mixture spectra, where the contribution of the components varies with a decaying exponential [B. Antalek and W. Windig, J. Am. Chem. Soc. 118, 10,331-10,332 (1996); W. Windig and B. Antalek, Chemom. Intell. Lab. Syst. 37, 241-254 (1997)]. The method was called DECRA (direct exponential curve resolution algorithm). In this paper DECRA will be applied to two series of magnetic resonance images. The signal of one series is based upon T2 relaxation, and the other is based upon T1 relaxation. In order to evaluate the technique, the magnetic resonance images of a phantom where used. A transformation is introduced to enable the application of DECRA to a T1 series of magnetic resonance images. A separate paper in this issue will describe the application of the techniques to magnetic resonance images of the human brain. Copyright 1998 Academic Press.

Journal Article↗
PubMed1998

Multivariate image analysis of magnetic resonance images with the direct exponential curve resolution algorithm (DECRA). Part 2: Application to human brain images.

Owing to the heterogeneity of living tissues, it is challenging to quantify tissue properties using magnetic resonance imaging. Within a single voxel, contributions to the signal may result from several types of 1H nuclei with varied chemical (e.g., -CH2-, -OH) and physical environments (e.g., tissue density, compartmentalization). Therefore, mixtures of 1H environments are prevalent. Furthermore, each unique type of 1H environment may possess a unique and characteristic spin-lattice relaxation time (T1) and spin-spin relaxation time (T2). A method for resolving these unique exponentials is introduced in a separate paper (Part 1. Algorithm and Model System) and uses the direct exponential curve resolution algorithm (DECRA). We present results from an analysis of images of the human head comprising brain tissues.

Adult↗