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Biomedical subjects

B Asklin

Publications and source records attributed to B Asklin.

8 recordsLinked to original sources
PubMed1993

Ureteral obstruction due to primary localized amyloidosis.

Localized amyloidosis of the ureter is a rare condition. There are only 27 cases reported. Because of the difficulty in differentiating between localized amyloidosis or other benign conditions and a malignant tumor many cases have led to nephroureterectomy. We report a case of a middle aged woman who had an almost complete obstruction of the right ureter caused by amyloidosis. Biopsies were taken via a ureteroscope prior to exploration of the ureter enabling the patient to be treated with local excision and ureteroneocystostomy instead of nephroureterectomy.

Amyloidosis↗
PubMed1989

Intravesical lidocaine in severe interstitial cystitis. Case report.

We report on a patient with a 2-year history of severe interstitial cystitis with disabling symptoms of painful urgency and urinary incontinence. The condition is characterized by a severe inflammatory reaction in the cystic wall and varying degrees of success for most therapeutic measures employed. Repeated vesical instillations of lidocaine in the urinary bladder relieved the patient from her pain and induced a long-lasting and potent anti-inflammatory effect on the cystic wall. Plasma lidocaine concentrations were below toxic levels and no adverse reactions were reported.

Administration, Intravesical↗
PubMed1984

The urethral pressure profile during flow. An experimental study.

As part of a project aimed at developing a method for accurate evaluation of the position and significance of infravesical outflow obstructions, a technique for recording urethral pressure profiles during flow in male patients was tested in a rigid bladder-urethral model. The catheter which proved to give the most accurate recording of the static pressure in the urethral model had a measuring eye about 250 mm from the tip. With this arrangement, the tip of the catheter did not leave the bladder until the measuring eye had passed the whole length of the urethra and the effective diameter of the urethra and the flow did not change during the recording. The pressure profiles for the different urethral models closely resembled the theoretically calculated curves. Furthermore, the constant recording conditions made it possible to compensate for the influence of the measuring catheter and to calculate the "true" diameter as well as the "true" resistance in different segments of the models.

Catheters, Indwelling↗
PubMed1984

The micturitional urethral pressure profile.

The micturitional urethral pressure profile (MUPP) was recorded using a measuring catheter with two eyes, 250 mm apart, one for recording the bladder pressure, the other for the urethral pressure during continuous withdrawal during micturition. Fifteen normal male subjects and 48 male patients with infravesical obstruction were studied. By means of the MUPP, it was possible to determine whether the patient had an obstruction or not, to differentiate between various kinds of obstructions and to localise the obstruction in the urethra. Provided infravesical obstructions can be considered "near rigid" segments, the degree of obstruction can be calculated and expressed in terms of a diameter and an approximate resistance. The diameter and resistance values should, however, not be considered alone but be regarded as complementary to the pressure profile.

Adult↗
PubMed1984

Functional evaluation of anterior urethral strictures with combined antegrade and retrograde urethrography.

The merits of radiological examination for functional evaluation of urethral strictures of the anterior male urethra were studied by comparing the results of combined retro- and antegrade urethrography with the patient's maximum urinary flow-rate. A correlation was found between stricture diameter and maximum flow-rate (r=0.67) and a still higher correlation between the ratio stricture diameter-prestenotic urethral diameter and the flow-rate (r=0.73). A low but significant (p less than 0.05) negative correlation was obtained between the prestenotic urethral diameter and the flow-rate (r=0.25).

Adult↗
PubMed1983

Visual internal urethrotomy with postoperative cystostomy or urethral catheter.

Visual internal urethrotomy is nowadays considered by many to be a very useful method of treating urethral strictures. There is still controversy, however, about how long the postoperative urethral catheter should be left in situ. A prospective randomised study was therefore performed to evaluate the influence on the results of urethral catheterisation versus a suprapubic cystostomy for 5 weeks. After 12-36 months of follow-up (mean 25 months) there was a significant difference in result in favour of the urethral catheter. In the catheterised group, 13 out of 20 patients were without recurrence, compared to 4 out of 17 patients in the cystostomy group. Of the total number of 76 patients treated by postoperative urethral catheterisation, 37 (48%) had a normal or slightly subnormal flow-rate 12-60 months after the urethrotomy. Young patients and patients with stricture treated for the first time showed significantly better results than older patients or patients who had previously been treated twice or more. The stricture diameter-prestenotic urethral diameter ratio, obtained by combined retrograde and antegrade urethrography, provided a fairly accurate measure of the functional significance of a stricture.

Adult↗
PubMed1978

Endourethral urethroplasty: a simple method for treatment of urethral strictures by internal urethrotomy and primary split skin grafting.

Primary endourethral split skin grafting was performed in 4 patients operated upon for stricture of the bulbous urethra by internal urethrotomy. Post-operatively, all grafts were found to have taken. Follow-up has ranged from 4 to 12 months. The results were considered good in all patients and after release from the hospital they had no subjective symptoms. Further urethral dilation has not been necessary in any of the patients.

Adult↗