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Biomedical subjects

B Atilla

Publications and source records attributed to B Atilla.

10 recordsLinked to original sources
PubMed2000

Scintigraphic evaluation of impaction grafting for total hip arthroplasty revision.

To determine the fate of an impacted allograft after a minimum follow-up of 1 year, we examined 9 of 40 patients who underwent revision arthroplasty with the impaction grafting technique. The allograft used in this study was morselized cancellous freeze-dried allograft. We examined these 9 patients with technetium-99 m methylene diphosphonate bone scintigraphy at an average of 14 (range 12-20) months after surgery. All of them had a good clinical outcome, with an average postoperative Hip Society Score of 89 (range 65-98) and no evidence of radiolucency or subsidence on direct radiography. Scintigraphic examination demonstrated that the area corresponding to the allograft had a remarkable radioactivity accumulation suggesting new bone formation. The allograft in total hip revision using the impaction grafting technique undergoes a significant neovascularization and new bone formation. This study suggests than when vigorous impaction is used, freeze-dried cancellous allograft can be used for impaction grafting.

Arthroplasty, Replacement, Hip↗
PubMed1997

The shape of the lumbar vertebral canal in newborns.

STUDY DESIGN: This study used geometric measurement criteria to assess the incidence of a trefoil spinal canal configuration in neonates. OBJECTIVES: To examine the shape of the neonatal lumbar vertebral canal with regard to its shape and the incidence of trefoilness. SUMMARY OF BACKGROUND DATA: Many studies consider the trefoil canal to be a developmental feature. Because of a lack of neonatal samples it is still unknown whether some individuals are prone to develop a trefoil spinal canal because of genetically determined factors. METHODS: The last two lumbar vertebrae of 31 term neonatal cadavers from the collection of the Anatomy Department of Ondokuz Mayis University were examined. After removal, the vertebrae were processed and embedded in paraffin blocks to enable accurate sectioning at the pedicle level. Subsequently, unmagnified images were obtained through a color photocopy machine. These two-dimensional images were digitalized, and accurate measurements were made to determine the circularity and the trefoilness. RESULTS: Trefoilness assessment indicated that the trefoil-shaped spinal canal does not exist in newborns. The spinal canal at this age is mostly dome-shaped. CONCLUSIONS: In accordance with the previous hypotheses made by other authors, the authors of this study found that the trefoil shape of the lumbar vertebra does not occur at the end of the intrauterine period.

Cadaver↗
PubMed1996

Spinal canal remodeling in burst fractures of the thoracolumbar spine: a computerized tomographic comparison between operative and nonoperative treatment.

Operative and nonoperative treatment methods of burst fractures were compared regarding canal remodeling. The entire series consisted of 18 patients, with seven in the operative treatment group and 11 in the nonoperative treatment group. All fractures were studied with computed tomography (CT) at the postoperative (operative treatment group) or postinjury (nonoperative treatment group) and the latest follow-up. All patients were followed up for > or = 18 months. There was no statistical difference between postoperative and postinjury canal areas (p = 0.0859). However, a significant difference was found between the rates of remodeling (p = 0.0059). Although spinal canal remodeling occurred in both groups, the resorption of retropulsed fragments was less favorable in nonoperative treatment group.

Adult↗
PubMedDate not supplied

In vitro/in vivo evaluation of the efficiency of teicoplanin-loaded biodegradable microparticles formulated for implantation to infected bone defects.

Chronic osteomyelitis is still the cause of many problems in orthopaedics in terms of therapy and infection persistence. Four-to-six week systemic antibiotic therapy is required along with bone and soft tissue debridement in the therapy of chronic osteomyelitis. Prolonged-release local antibiotic therapy has been taken into consideration due to the side effects encountered in long-term high dose antibiotic use and the duration of hospitalization of the patients. Although local antibiotic therapy has been achieved by bone cement, a second surgical operation is needed for the removal of the system. On the other hand, heat generation during cement curing limits the use of heat-sensitive active ingredients. The most frequent osteomyelitis inducing micro-organism is gram (+) Staphylococcus aureus. In this study, teicoplanin, a glycopeptide antibiotic, active on gram (+) bacteria, was incorporated in a synthetic polymer in order to prepare a microsphere formulation for implantation to bone defects. Particle size, surface characteristics, loading capacity and in vitro release characteristics of the microspheres were determined as well as stability assessment of teicoplanin under accelerated conditions. In vivo studies were performed on rabbits and the microparticles were implanted intra-articularly to the lateral condylus of the femur. Antibiotic presence was detected by a microbiological assay from synovial fluid sample aspirated throughout 5 weeks. In the light of these evaluations, microspheres prepared from PLGA (75:25) (Mw 136,000) polymer were determined to be effective, and promising for obtaining prolonged local antibiotic release.

Animals↗
PubMedDate not supplied

Rotational profile of lower extremities in bladder exstrophy patients with unapproximated pelvis: a clinical and radiologic study in children older than 7 years.

Fourteen patients (nine boys, five girls) with bladder exstrophy were analyzed radiologically and clinically. All were older than 7 years and had a pubic diastasis >2 cm. Anteroposterior and lateral center-edge angles were measured by direct radiography. Acetabular version, femoral anteversion, tibial torsion angles, and patellofemoral congruency angle were measured by computed tomography imaging. All were active with regard to their daily life and sports activities. The average foot-progression angle was +8 degrees . Spherical congruency was present in all hips, and none showed dysplasia. The average angle of acetabular version was apparently less than normal, but femoral anteversion angles were found to be increased. Increased external tibial torsion was observed in all patients. Twelve (71%) of 14 patients had positive congruence angles, the average being +6.1 degrees . Two patients had subjective complaints of patellofemoral instability. Increased femoral anteversion and external tibial torsion may lead to patellofemoral instability, and the bladder exstrophy patients should be followed up regarding this problem as well.

Adolescent↗
PubMedDate not supplied

Unilateral late-onset tibia vara associated with bilateral proximal femoral growth disturbance in monozygotic twins: case report.

Clinical and histopathological similarities and rare association of Blount's disease with various proximal femoral physeal affections (i.e. adolescent coxa vara and slipped capital femoral epiphysis) are well known. Association of tibia vara with another epiphyseal disease of the proximal femur has not been reported previously. In this paper, a monozygotic set of twins with concordant bilateral epiphyseal growth disturbance of the proximal femur and unilateral late-onset tibia vara is presented. Radiological characteristics of the affected knees revealed a wedging in the proximal tibial epiphysis, depression of the medial joint surface and varus deformity of the tibia. Proximal femurs of both cases showed aspheric congruity, coxa magna, shortness of the femoral neck, and subchondral cystic changes. The presented cases support the genetic etiology of tibia vara, and association of the two conditions is unique.

Adolescent↗
PubMedDate not supplied

Risk factors associated with corrective surgery in congenital scoliosis with tethered cord.

Severe neglected congenital scoliosis with tethered cord presents major difficulties in management. The primary objective of this study was to identify the risk factors associated with corrective scoliosis surgery in neglected cases presenting with severe deformity. Six patients who presented with such problems draw attention to the importance of a staged anterior and posterior approach in order to obtain satisfactory functional results. However, corrective surgery is associated with major neurologic and systemic complications, and every effort should be made to intervene with the progression of the deformity before corrective measures becomes necessary.

Adolescent↗