B Azmon | PubMed Health

PubMed2003

Area-specific amblyopic effects in human occipitotemporal object representations.

The role of early visual experience in the establishment of human high-order visual areas is poorly understood. Here we investigated this issue using human amblyopia--a developmental visual disorder, which manifests a central vision (acuity) deficit. Previous fMRI studies of amblyopes have described abnormal functional activations in early retinotopic areas. Here we report the surprising finding of a selective object-related abnormality in high-order occipitotemporal cortex. Specifically, we found that face-related cortical areas show a severe disconnection from the amblyopic eye, while building-related regions remain essentially normal. The selectivity of the deficit highlights the differential computations performed in the different object-related areas and is compatible with the suggested association of face regions with analysis of fine detail.

Acoustic Stimulation↗

PubMed1999

Effectiveness of sub-Tenon's versus peribulbar anesthesia in extracapsular cataract surgery.

PURPOSE: To compare the effectiveness of sub-Tenon's versus peribulbar anesthesia in extracapsular cataract surgery. SETTING: Department of Ophthalmology and the Maccabi Eye Institute, Tel Aviv, Israel. METHODS: Sixty-four consecutive patients who had extracapsular cataract surgery were randomized to have sub-Tenon's or peribulbar anesthesia. Intraocular pressure (IOP) was measured before and 1 and 10 minutes after injection. The motility of the rectus muscles was evaluated before and 20 minutes after the injection, and the patient's anxiety level was recorded immediately after the injection. Pain was assessed intraoperatively and 1 and 24 hours postoperatively by patient self-grading. RESULTS: One minute after the injection, IOP increased significantly in the peribulbar group (mean 7.97 mm Hg +/- 8.80 [SD]) (P < .05). There was no significant increase in the sub-Tenon's injection group (mean 0.12 +/- 3.09 mm Hg). In both groups, IOP returned to preinjection levels by 10 minutes postoperatively. Patients with peribulbar anesthesia reported a significantly higher level of anxiety than those who had sub-Tenon's anesthesia (P < .05). Although the intraoperative pain levels were the same, the sub-Tenon's group reported significantly higher levels of pain 1 and 24 hours postoperatively; 16% in the sub-Tenon's group and none in the peribulbar group reported moderate pain 24 hours after anesthesia. Ocular motility was the same except for the inferior rectus muscle, which was less motile on average in the peribulbar group. CONCLUSION: Sub-Tenon's anesthesia led to less IOP elevation than peribulbar anesthesia and provided similarly good globe immobilization and approximately the same pain levels intraoperatively.

Adult↗