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Biomedical subjects

B B Beiswanger

Publications and source records attributed to B B Beiswanger.

32 records · Page 2Linked to original sources

Effects of nicotine-containing chewing gum on oral soft and hard tissues: A clinical study.

A double-blind clinical trial was conducted to determine whether the use of a chewing gum containing 2.0 mg nicotine (as an adjunct to a stop-smoking program) had any effects upon oral health. A total of 193 adults who smoked cigarettes volunteered with informed consent, were given routine dental prophylaxes, and were examined for the presence of plaque, stained pellicle, gingivitis, calculus, and general oral pathosis. The subjects were then randomly assigned to use either a nicotine-containing or a placebo chewing gum. After 15 weeks the subjects were recalled and re-examined. Smoking cessation was determined through questionnaire and analysis of the carbon monoxide content of alveolar air. At the completion of the study, 79 subjects had used the placebo gum and 78 had used the nicotine gum. Data analysis indicated that the nicotine chewing gum had no significant influence on any of the oral health parameters graded, as compared to the placebo gum. The continuation of smoking, however, was associated with significant increases in gingivitis and calculus rates.

Carbon Dioxide↗

Comparisons of various salivary parameters in smokers before and after the use of a nicotine-containing chewing gum.

This study was designed to compare various salivary parameters between smokers and non-smokers and to determine the influence of a nicotine-containing chewing gum (used to aid in quit-smoking efforts) upon these same parameters. At the baseline examination, subjects were assigned to one of three groups: non-smokers who did not utilize any gum, smokers provided a nicotine-containing gum, and smokers provided a placebo gum. Saliva was collected from all subjects and analyzed for acidogenicity and buffer pH as well as for levels of thiocyanate, lactoperoxidase, lysozyme, lactoferrin, and secretory IgA. After 15 weeks of gum usage, saliva was again collected from each subject and the identical analyses performed. Significant differences were observed between smokers and non-smokers with regard to three parameters: The saliva of smokers contained greater concentrations of thiocyanate and lower concentrations of lactoferrin, at the baseline examination and after the 15-week test period. In addition, the CO content of alveolar air was higher in smokers at both examination periods. In contrast, the use of the nicotine gum per se had no effect on any of the test parameters.

Adult↗

A three-year study of the effect of a sodium fluoride-silica abrasive dentifrice on dental caries.

The purpose of this study was to determine if a 0.243% sodium fluoride-silica abrasive dentifrice provides greater anticaries efficacy than a 0.4% stannous fluoride-calcium pyrophosphate abrasive dentifrice. A sample of 1,824 schoolchildren was randomly assigned to either the sodium fluoride dentifrice or the stannous fluoride dentifrice and examined clinically and radiographically for dental caries initially and after one, two, and three years of dentifrice usage. Two examiners independently examined each of the subjects for dental caries. After three years of ad libitum dentifrice usage, the results for both examiners showed that the group brushing with the sodium fluoride dentifrice had significantly lower DMF tooth and DMF surface increments than the group brushing with the stannous fluoride dentifrice. The percent reductions for DMF teeth were 14.8% and 10.5%, and for DMF surfaces 16.4% and 13.1% for the two examiners, respectively.

Adolescent↗

A clinical caries evaluation of a stannous fluoride prophylactic paste and topical solution.

A three-yr caries study was conducted to evaluate an SnF2 prophylactic paste and topical solution professionally applied to children on a semi-annual basis. The topical solution imparted a significant decrease in caries incidence while the prophylactic paste was without significant effect. The combination of treatments was not significantly more effective than the topical application alone.

Adolescent↗

Influence of an experimental sodium fluoride dentifrice on dental caries incidence in children.

Schoolchildren residing in a fluoride-deficient area were provided either a sodium fluoride (0.1% F) or a nonfluoride dentifrice for home use. About half the children provided each type of dentifrice were also given an initial prophylaxis. Combining the data with regard to the type of dentifrice indicated that the sodium fluoride dentifrice resulted in dental caries reductions of 24 and 26% as noted by the two examiners, respectively.

Adolescent↗

Method for the clinical evaluation of enamel polish.

Enamel polish of 600 children was scored. The method used is simple and comprises a visual comparison of the facial surfaces of incisors with a polish standard prepared by selectively polishing extracted teeth. Examiners with little experience can distinguish degrees of enamel polish. A high-polish dentifrice produced significantly greater enamel polish during the 27-month study. A "polish" with flour of pumice at the beginning of the study did not influence this enamel polish.

Adolescent↗

Mouthwash and oral cancer.

Recently, a small but significant relationship has been identified between the use of over-the-counter mouthwash preparations containing greater than 25 percent alcohol and the development of oral cancer. This paper reviews the medical and dental literature, discusses the implications of long-term, excessive mouthwash use and makes recommendations regarding the use of mouthwash with a high alcohol content.

Animals↗

The comparative clinical cariostatic efficacy of sodium fluoride and sodium monofluorophosphate dentifrices: a review of trials.

This report reviews the methods and findings of published clinical studies comparing dentifrices containing sodium fluoride (NaF) and sodium monofluorophosphate (Na2PO3F) for the purpose of determining whether sodium fluoride formulations have superior cariostatic effects. Nine of ten reported trials found a numerical advantage for sodium fluoride dentifrices with highly compatible abrasive systems and the hypothesis that these two fluoride agents have equivalent cariostatic effects is rejected (p = 0.011). Therefore, the collective clinical evidence demonstrates that dentifrices containing NaF have greater cariostatic effectiveness than dentifrices containing Na2PO3F.

Calcium Pyrophosphate↗

Effects of nicotine chewing gum on complete dentures and their soft-tissue-bearing areas.

One hundred six edentulous subjects were given nicotine-containing chewing gum to evaluate the ability to chew the gum, to observe the adherence of the gum to denture-base materials, and to evaluate the effect of gum chewing on denture-bearing tissues. Prior to the 13-week study, the denture-bearing ridges and the tissue and polished surfaces of the denture were evaluated clinically and photographed. Questionnaires were used to elicit personal habits of the subjects. Of the 59 subjects completing the study, most could manipulate and chew the gum effectively, three-fourths reported that gum adherence was not a problem, and no adverse reaction to oral tissues was observed.

Adhesiveness↗

A clinical evaluation of the relative cariostatic effect of dentifrices containing sodium fluoride or sodium monofluorophosphate.

A three-year clinical trial was conducted to determine whether a sodium fluoride (NaF) dentifrice had greater cariostatic effects than a sodium monofluorophosphate (Na2PO3F) dentifrice. Both dentifrices contained 1100 ppm fluoride and silica abrasive systems. A panel of 3,290 children, age 6-16, received one of the two dentifrices for ad libitum home use. The subjects were examined for caries at the baseline and after 2 and 3 years. Results were analyzed both for all children and for those children age 11 years or older at the baseline. The older children were found to have about 50 percent higher new caries increments than did the entire panel of children. In the older, caries- prone children, the subjects using the NaF product experienced significantly (15 percent and 12 percent) fewer new lesions than did the subjects using the Na2PO3F product after 2 and 3 years respectively. In the panel of all children, subjects using the NaF product had numerically, but not significantly, fewer new lesions. The results for this study, showing significantly greater cariostatic benefits in caries-prone children for a sodium fluoride dentifrice with a highly compatible system, are consistent with findings of other investigators.

Adolescent↗