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Biomedical subjects

B B Berger

Publications and source records attributed to B B Berger.

At least 19 recordsLinked to original sources
PubMed1993

Miliary toxoplasmic retinitis in acquired immunodeficiency syndrome.

A unique pattern of bilateral miliary retinitis due to ocular toxoplasmosis developed in a patient in the late stages of acquired immunodeficiency syndrome. Results of serologic tests for toxoplasmosis remained negative throughout the clinical course of his ocular disease. The retinitis was unresponsive to a brief course of anti-toxoplasmosis therapy. At autopsy, the histopathologic material was consistent with toxoplasmic retinitis and the DNA polymerase chain reaction was positive for toxoplasmosis. Recognition of this pattern of retinitis is important in the appropriate treatment of immunosuppressed patients with retinitis.

AIDS-Related Opportunistic Infections↗
PubMed1988

Ocular toxoplasmosis in patients with the acquired immunodeficiency syndrome.

In seven of eight cases of presumed ocular toxoplasmosis in patients with AIDS, the diagnosis was supported by a reduction or resolution of intraocular inflammation and healing of necrotic retinal lesions after initiation of antiparasitic drug therapy including one or more of the following medications: pyrimethamine, sulfadiazine, clindamycin, tetracycline, or spiramycin. In two cases the diagnosis was confirmed histologically. The cases differed clinically and histopathologically from those in immunocompetent patients. There was no evidence that disease originated in preexisting retinochoroidal scars. Lesions frequently were bilateral and multifocal. Vitreous inflammatory reaction was a common clinical finding, but histopathologic examination demonstrated scant retinal inflammation in areas of necrosis. Ocular toxoplasmosis in these patients with AIDS probably resulted from newly acquired infection or dissemination of organisms from nonocular sites of disease. Infections became clinically inactive with drug therapy in all treated patients, but reactivation and progression of disease occurred when therapy was stopped in two of three patients. Severe retinal necrosis led to retinal tears or detachment in three cases. Ocular lesions were the first manifestation of Toxoplasma gondii infection in four of five patients with evidence of multisystem infection.

Acquired Immunodeficiency Syndrome↗
PubMed1984

Foveal photocoagulation from laser iridotomy.

Acute and permanent loss of vision has resulted from foveal photocoagulation during argon laser iridotomy. This complication can occur when the laser beam passes through the iridotomy nearly parallel to the visual axis. This is most likely to happen during enlargement of the iridotomy. A retinal burn of the macular region through a peripheral iridotomy was produced experimentally, and the mechanism of this complication is explained.

Animals↗
PubMed1984

Branch vein occlusion: traction macular detachment.

Traction detachment of the macula from extensive disc neovascularization developed after a branch vein occlusion. This rare complication was effectively treated by vitrectomy with membrane segmentation.

Constriction, Pathologic↗
PubMed1982

Prostatic carcinoma metastatic to choroid.

Metastatic prostatic carcinoma of the choroid became clinically undetectable after orchidectomy and oestrogen administration. The choroidal tumour rapidly regressed over a 2-month period and clinically disappeared, with restoration of 6/6 vision from 6/60 and return of visual field. This dramatic response and lack of complications make hormonal manipulation the preferred mode of initial therapy in prostatic carcinoma metastatic to the choroid.

Adenocarcinoma↗
PubMed1980

Anterior segment ischemia in Fuchs' heterochromic cyclitis.

Six consecutive patients with early Fuchs' heterochromic cyclitis (FHC) were examined with anterior segment 10% fluorescein sodium angiography. Anterior segment perfusion defects and iris vasculature leakage were seen in all patients. Chronic anterior segment ischemia may be an integral feature of FHC, which predisposes these eyes to rubeosis and, in some cases, to neovascular glaucoma.

Adolescent↗
PubMed1980

Vitreous loss managed by anterior vitrectomy. Long-term follow-up of 59 cases.

Fifty-nine cases of vitreous loss managed by anterior vitrectomy were followed up for an average of 26 months. Thirty-seven cases were managed by automated anterior vitrectomy and 22 by cellulose sponge anterior vitrectomy. Both techniques, when performed by resident ophthalmologists, give equivalent results. Anterior vitrectomy for vitreous loss gives significantly better results than nontreatment of vitreous loss but significantly poorer results than uncomplicated intracapsular cataract extraction. This is largely caused by the increased incidence of chronic cystoid macular edema after vitreous loss. Vitreous loss treated by anterior vitrectomy is associated with 10% to 15% greater endothelial cell loss than uncomplicated intracapsular cataract extraction.

Cataract Extraction↗
PubMed1979

Bilateral cytomegalovirus panuveitis after high-dose corticosteroid therapy.

A 30-year-old previously healthy woman who recieved immunosuppressive doses of corticosteroids developed an unusual culture-proved cytomegalovirus panuveitis bilaterally. The atypical clinical course was marked by bilateral exudative detachements with minimal evidence of retinitis. Any patient receiving blood transfusions and immunosuppressive doses of corticosteroids is potentially at risk for developing ocular cytomegalovirus infection, and the clinical presentation of the ocular infection may be atypical.

Adult↗