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Biomedical subjects

B B Evans

Publications and source records attributed to B B Evans.

At least 19 recordsLinked to original sources

Opacification of piggyback IOLs associated with an amorphous material attached to interlenticular surfaces.

PURPOSE: To report the pathological and ultrastructural features and interval surgical management of an atypical case of opacification between piggyback intraocular lenses (IOLs). SETTING: Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, and Nature Coast EyeCare Institute and Surgery Center, Perry, Florida, USA. METHODS: Opacification between 2 acrylic piggyback lenses was observed 16 months after implantation, with decreased best corrected visual acuity and a hyperopic shift. Elschnig pearls were observed in the peripheral interface between the lenses, and the central interface was occupied by an amorphous material. The pearls were surgically aspirated, but attempts to remove the central material were unsuccessful. The lenses were explanted and sent to the laboratory. Staining with hematoxylin and eosin (H&E), examination under a light microscope, and scanning electron microscopic analysis were performed. RESULTS: The surfaces of the anterior IOL were relatively clear. The amorphous material, mostly attached to the center of the anterior surface of the posterior IOL, was homogeneously stained with H&E. No cell nucleus was observed in this region. Scanning electron microscopy showed that the IOL edge presented a smooth, regular surface relatively free of deposits. The most central region was covered by an irregular layer of an amorphous compact material with some cracks, fissures, or both on its surface. CONCLUSIONS: Although the exact composition of the material between the lenses could not be established, hypotheses were advanced to understand the pathological mechanism associated with this condition. This case is different from those in previous reports of opacification composed of cortex and cells between piggyback IOLs.

Acrylates↗

Evaluating predictors and concomitants of patient health visit satisfaction: an empirical study focusing on methodological aspects of satisfaction research.

We propose that the weak and conflicting results from various studies of satisfaction concomitants are due to the use of scales which sum scores from items that measure different types of satisfaction. The hypothesis is clearly supported, leading to the strong recommendation that different types of patient satisfaction be studied separately. Implications for studying and potentially increasing patient satisfaction are discussed.

Ambulatory Care Facilities↗

Correction of intrinsic penile chordee with a ventral penile graft of fascia lata.

Chordee is an abnormal curvature of the penis detected on erection. Congenital or primary curvature of the penis without hypospadias is, however, rare. There are two kinds of primary curvatures; those associated with a normal corpus spongiosum and those with a hypoplastic spongiosum. Secondary curvatures associated with Peyronie's disease or periurethral fibrosis associated with urethral stricture are more common in adults. Four nonhuman primates had successful correction of artificially induced chordee with a graft of fascia lata.

Animals↗

Ureteropelvic junction obstruction: the effect of pyeloplasty on renal function.

We studied preoperatively and postoperatively 41 children who underwent pyeloplasty for correction of unilateral ureteropelvic junction obstruction. Conventional radiological studies and quantitative radioiodine hippurate renal scans were obtained to assess the effect of pyeloplasty on the appearance of the kidney and its function. Analysis of the data suggests that the degree of improvement in renal function is related primarily to the age at which the surgical correction is accomplished and whether infection has occurred preoperatively.

Adolescent↗

The renal quantitative scintillation camera study for determination of renal function.

The renal quantitative scintillation camera study assesses glomerular filtration rate and effective renal plasma flow based upon renal uptake of 99mtechnetium-iron ascorbate and 131iodine-hippuran, respectively. The method was compared to inulin, para-aminohippuric acid and creatinine clearance studies in 7 normal subjects and 9 patients with various degrees of reduced renal function. The reproducibility of the technique was determined in 15 randomly selected pediatric patients. The values of glomerular filtration rate and effective renal plasma flow were not significantly different from those of inulin and para-aminohippuric acid studies. The reproducibility of the technique was comparable to that of inulin and para-aminohippuric acid studies. Patient acceptance of the technique is excellent and the cost is minimal. Renal morphology and excretory dynamics also are demonstrated. The technique is advocated as a clinical measure of renal function.

Adolescent↗

Renal quantitative scintillation camera studies in the management of myelodysplasia.

The renal quantitative scintillation gamma camera study has been used in the evaluation and management of 95 children with myelodysplasia. This study has been helpful in assessing renal function. The precise information, reproducibility of results, high correlation with excretory urography and a minimal amount of irradiation exposure to the patient make this procedure an ideal technique to evaluate and follow a population that needs continuous monitoring of individual as well as total renal function.

Adolescent↗

Lymphatic neovascularization after orchiopexy.

Lymphatic neovascularization after transseptal and ipsilateral orchiopexy was studied in dogs. After the former, massive scrotal and inguinal lymphatic neovasculature developed on the side of the subcutaneous pouch; the lymphatic vessels drained into both right and left superficial inguinal, iliac, and paraaortic lymph nodes. After ipsilateral orchiopexy, neovascularization was confined mainly to the scrotum and inguinal areas of the affected side, although crossing to the opposite inguinal nodes was also seen. In the unoperated animal the lymph of the testicle was partially drained through the lymphatics of the epididymis and vas deferens into the iliac nodes.

Animals↗

Displacement of left kidney suggesting adrenal tumor.

Several infants with a left suprarenal "cold spot" shown on technetium scintiphotos were also found to have inferior displacement of the left kidney on the urogram. Surgical exploration was considered on the basis of possible adrenal tumor; however, the highly suspicious "lesion" disappeared after gastric deflation, and it was recreated after gastric distention. Review of infant urograms has shown that gastric distention is a common cause of a "normal" low-lying left kidney, in clear distinction to the adult in whom a displaced left kidney frequently shows a pathologic condition.

Adrenal Gland Neoplasms↗

Cerebrospinal fluid pseudocyst after urinary diversion.

The development of an abdominal mass after urinary diversion in a patient with a ventriculoperitoneal shunt should alert the physician to the possibility of a cerebrospinal fluid pseudocyst. Two pediatric cases of cerebrospinal fluid pseudocysts are presented to illustrate this complication. The etiology, diagnosis and management of the pseudocyst are discussed and the literature is reviewed.

Abdomen↗

Management of severe hydroureteronephrosis in infants and young children.

Loop cutaneous ureterostomy and cutaneous pyelostomy are safe and effective means of temporary diversion with few complications. Reconstructive operation is delayed until the upper urinary tract has shown maximum improvement in form and function and the patient's tolerance for elective operation has improved. Results of reconstruction may be less than optimal and serious complications may arise. However the staged approach has been shown to be safe and effective. Experience with 29 patients has led to a reassessment of the approach to patients with posterior urethral values and a stronger inclination to primary valve resection, thus avoiding many of the reconstructive procedures ultimately associated with temporary diversion. Patients with posterior urethral valves who have hydronephrotic upper urinary tracts, normal or near normal serum chemistry studies and are free of infection may receive initial valve ablation. All patients with massive hydroureteronephrosis require long-term followup to ensure preservation of renal function regardless of the approach used.

Child, Preschool↗

131I hippuran quantitative scintillation camera studies in the evaluation and management of vesicoureteral reflux.

A study was made of 136 patients with vesicoureteral reflux with the conventional radiologic modalities of voiding cystourethrography and IVP. In addition, a 30-minute quantitative scintillation camera study was used. Comparison of these studies indicates that most periodic re-evaluations with IVP can be eliminated in favor of the scintillation study with its markedly reduced radiation dosage and lack of allergic type reactions. Unfortunately, as the quantitative scintillation camera study has been performed in these patients, it has been impossible to diagnose the presence of vesicoureteral reflux. Therefore, voiding cystourethrography or direct radionuclide cystography must be repeated at some time to determine if conservative management has been successful. The benefit of the routine use of the quantitative scintillation camera study in the early postoperative period seems to be strongly supported even by the small group of patients studied.

Evaluation Studies as Topic↗