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Biomedical subjects

B Babudieri

Publications and source records attributed to B Babudieri.

At least 19 recordsLinked to original sources
PubMed1973

Comparative tests with formolized and irradiated vaccines against leptospirosis.

The effectiveness of gamma-irradiated antileptospirosis vaccines and of vaccines killed with formol was compared in guineapigs. Irradiated vaccines proved no more effective than formolized vaccines in preventing either death or persistent kidney infection. Anti-pomona vaccines gave little protection against serotype icterohaemorrhagiae, and there was no significant difference between irradiated and formolized preparations. Vaccine prepared from a virulent strain showed little advantage over vaccine prepared from weak strains.

Animals↗
PubMed1972

Mycoplasma-like organism, parasite of red blood cells of an amphibian, Hydromantes italicus (Spelerpes fuscus).

In the present investigation we studied a parasite of red blood cells in the amphibian Hydromantes italicus. The parasite, a globular microorganism having a diameter of 0.25 to 0.3 mum, was found in large numbers in vacuoles of red blood cells. As seen by electron microscopy, it possesses no cell wall and has the morphological appearance of a mycoplasma. The parasite has great motility by mechanisms not yet elucidated. It is possible to transmit the infection experimentally from infected to healthy amphibians. Culture of the microorganism, named Chondrostagon haematicum, in artificial media has not yet been successful.

Amphibians↗
PubMed1972

Research needs in leptospirosis.

Leptospirosis is a widespread infection of man and animals, and locally it assumes considerable importance as a public health and economic problem. It is an important occupational infection among persons working with animals or in environments that may be contaminated by infected animals. In recent years, considerable attention has been devoted to this infection but efforts to control and eliminate it, especially from natural foci, are hindered by gaps in our knowledge. This memorandum is a review of recent progress and current problems in leptospirosis research, with special reference to taxonomy, epidemiological methods, and control measures. Certain aspects of the basic biology of leptospires that are relevant to these topics are also discussed.

Agglutination↗
PubMed1971

Proposed standardization of the agglutination-adsorption test for Leptospira.

The systematics of the Leptospira is based on the agglutination test and on the cross-agglutination-adsorption test. To obtain reproducible and comparable results these tests must be carried out by standard techniques, but the accuracy of the tests is in any case limited since immune sera prepared from animals do not always react uniformly. Moreover, the micro-organisms used in the tests have specific requirements and do not always develop properly in synthetic media. The various factors that influence the results of agglutination-adsorption tests were investigated and evaluated. Taking the results of these studies into account, a standardized method for agglutination-adsorption tests is proposed and described.

Adsorption↗