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Biomedical subjects

B Belkin

Publications and source records attributed to B Belkin.

3 recordsLinked to original sources

Intra-arterial fibrinolytic therapy. Efficacy of streptokinase vs urokinase.

This study is a retrospective comparison of the results in 25 low-dose, intra-arterial streptokinase and 12 low-dose intra-arterial urokinase infusions for thromboembolic disease. Intra-arterial streptokinase was successful in 50% of infusions and was marked by significant abnormalities in the coagulation criteria. There was a high incidence of major and minor bleeding (48% overall), which could be attributed to systemic effects of the drug. Urokinase was successful in 100% of infusions, and showed no significant effects on systemic coagulation criteria. There were also fewer complications during urokinase infusion. The average pharmacy cost for a course of intra-arterial streptokinase was $165, while urokinase cost $1142. Despite the significant difference in expense, the increased efficacy and safety of urokinase make it the preferred agent for intra-arterial infusion. Theoretical reasons for the increased effectiveness of urokinase are discussed.

Adult↗

Contribution of the depressive perspective to memory function in depression.

The authors used a story recall paradigm to elucidate some aspects of the memory problems of depressive patients. They compared 21 hospitalized depressed patients with a matched group of control subjects for recall of a theme story containing material with positive, negative, and neutral affective tones. The results indicated an overall deficit in the story recall of the depressed patients, most of which could be ascribed to a decrement in recall of the positive themes in the story. Recall of the negative and neutral themes remained intact. These results are consistent with the view that a depressive perspective contributes one component to the memory difficulties of depressed patients.

Adult↗

Memory deficits in depression: evidence utilizing the Wechsler Memory Scale.

The performance of 21 hospitalized depressed patients was compared to a matched group of 21 controls on the Wechaler Memory Scale. The depressed patients showed deficits on Mental Control, Verbal Learning, and Visual Reproduction tasks, which indicate impairment of memory functions in depression. There may be a deficit in the attention and alerting mechanism of depressed patients.

Adult↗