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Biomedical subjects

B Beyer

Publications and source records attributed to B Beyer.

26 records · Page 2Linked to original sources
PubMed1982

[The "Perthes-Braun-syndrome". A sign of severe blunt thoracic trauma in childhood].

"Perthes-Braun-Syndrom" is told to be sign of severe blunt thoracic trauma. We report about 7 patients up to the age of 14 years, who showed symptoms of thoracic compression. The syndrome appears in different expression with main symptoms as subconjunctival bleedings and petechias of the upper part of the body. In 6 of the described cases the syndrome was associated with severe intrathoracic lesions. In is concluded that intensive supervision is indicated in patients with "Perthes-Braun-Syndrome" because of delayed appearance of cardial and pulmonary symptoms.

Adolescent↗
PubMed1981

[Bacterial elimination and antibiotic concentration in the gall-bladder during biliary tract infections treated with mezlocillin (author's transl)].

A transpapillary indwelling catheter was placed in 15 patients with choledocholithiasis and threatened occlusion by stone. Ten of the 15 patients had marked biliary stasis, four had signs of acute cholangitis. In all patients E. coli was present in the gall-bladder in a concentration of greater than or equal to 10(5)/ml when the catheter was first inserted. The bacteria were sensitive to mezlocillin, at a minimal inhibitor concentration between 1.5 and 16 micrograms/ml. All patients received mezlocillin, 5 g twice daily, in a short-term infusion. Immediately before and regularly thereafter bile samples were taken to measure antibiotic concentration and bacterial counts (by membrane filtration). Mezlocillin was excreted in the bile in very high concentrations in patients without biliary stasis. But while the concentrations were markedly lower in those with stasis, they were still 10 to 100 times the minimum inhibitory concentration of mezlocillin against the appropriate strains. In keeping with the high mezlocillin concentration, bacterial counts fell much more quickly in the patients without stasis than in those with alkaline phosphatase concentration above 250 U/l. These differences were even more marked after two or three days. Bacterial elimination from bile was complete in two of three patients with normal alkaline phosphatase activity, but in only one of five in whom it was elevated.

Aged↗
PubMed1981

Synthesis and study of the potential antiallergic activity of some pyrazole derivatives.

The synthesis and study of the oral antiallergic activity of a series of monopyrazole derivatives (2-14) considered as analogues of active bispyrazole 1 are described. None of the compounds showed significant inhibition of the rat passive cutaneous anaphylaxis (PCA), with the exception of the already known 5-aminoindazole (2). The activity of this compound, is however, lower than that of compound 1.

Animals↗
PubMed1980

Synthesis of potential antiprogestins II.

Alkylated derivatives of 17-acetoxyprogesterone were prepared in order to test the hypothesis that bulky groups in certain positions of the steroid molecule have the effect of transforming progestogens into antiprogestogens. These groups might exert binding influence outside the area occupied by progesterone itself. The compounds were tested for competitive affinity against tritiated progesterone and receptor from rabbit uterus cytosol. The low affinity of all derivatives makes it unlikely that they would be active as antiprogestational agents.

Animals↗
PubMed1979

[Enzyme arrangement of various tissues in swine. 3. Studies of pre- and postnatal activities of various enzymes (ATPase, GOT, GPT, leucine aminopeptidase, acid and alkaline phosphatases, aldose reductase, glucuronate reductase, sorbitol dehydrogenase) in various tissues].

The crude protein levels as well as the activities of various enzymes were studied in certain tissues of fetuses (80th through 114th days of development), piglets of different age groups, and pigs for slaughter. In most of the tissues tested the postnatal activities of Na-K-ATPase were beyond those recorded from fetuses. The highest GOT activities were recorded from the liver, myocardium, and kidneys. Activities were found to rise sizeably in some tissues after birth. The activity of GPT, too, exhibited age-dependent variations. The activity of leucine-aminopeptidase increased strongly after birth in liver and kidneys. Acid phosphatase activity was less markedly influenced by development phases. Those enzymes which are involved in the formation of fructose and glucose (aldolreductase, glucuronate-reductase, and sorbite-dehydrogenase) had their highest activities, all age-dependent, in liver and kidneys.

Acid Phosphatase↗
PubMedDate not supplied

The politics of the health district reform in the Republic of Benin.

The analysis of health policy reform focuses mostly on the contents of reforms. Walt and Gilson (1994) draw attention to the fact that the environmental context as well as the actors involved are of crucial importance to the process of policy adoption. This paper describes and analyses the process of adoption of the new concept of so-called 'sanitary zones' in the Republic of Benin as part of the health sector reform. The analysis of the reform is based on the examination of documents and interviews carried out in Benin in February 1997. The main findings show that the reasons for the specific policy choice do not emerge clearly. The main problems identified are: the role of the hospital, the incongruous administration, resistance against the reform and the question whether the government actually has the political will to change. Possible solutions to these constraints are offered in the conclusion.

Benin↗
PubMedDate not supplied

[Between isolation and new hope: the psychosocial status of HIV-infected women].

HIV-infected women were an increasingly larger group among the risk groups in Germany. In order to illuminate the psychological situation of HIV-infected women in Germany, 100 women with HIV disease were enrolled in a basic study. 72% of the patients were intravenous drug addicted, 28% were infected through other means. The study population comprised patients of all stages of infection. We found 52% in the first stages, 28% in ARC and 20% with AIDS. Evaluated data included medical, socio-demographic, and data regarding the patients' history of drug abuse. The SCL-90-R, a psychological symptom inventory, was applied. Questions about differences between the two groups of HIV-infected women (iv drug addicted vs non-drug addicted) were answered first. Second, we described three clusters of HIV infected women with regard to different levels of psychological distress. Important factors to distinguish between these clusters are the subjective impact of physical distress (e.g. suffering from HIV-associated symptoms) and loss of joy and interest in sex. In order to illuminate the psychosocial situation, we discuss the specific situation of three patients.

AIDS-Related Complex↗