Cold tolerance in CCl4-treated rats and its modification by administration of garlic oil and glucose.
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Biomedical subjects
Publications and source records attributed to B Bhatia.
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Myocardial necrosis was induced in male Wistar rats by isoproterenol as described by Rona et al. (17). The treated animals had higher hypoxic tolerance than the controls when tested in a low pressure chamber (atmospheric pressure: 200 mm Hg) 24 hr and 2 weeks, respectively, after the second injection of isoproterenol. Prior adrenalectomy, but not adrenalmedullectomy, eliminated the effect of isoproterenol on hypoxic tolerance. The mean plasma cortisol level was significantly raised after isoproterenol treatment. Exposure to hypoxia also increased the plasma cortisol levels, in the normal as well as in the isoproterenol-treated animals.
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Standard measurements of water vapor conductance in units of mg of H(2)O . day(-1) . torr(-1) (SI equivalent is mg of H(2)O . day(-1) . pascal(-1)) of fresh eggs of the red-winged blackbird (Agelaius phoeniceus) and the native chicken of India (Gallus gallus) collected at altitude are significantly less than those of eggs of the same species collected near sea level. This decrease is caused by a reduction of the total effective pore area of the eggshell at altitude. It appears to be proportional to the reduction in barometric pressure and the simultaneous increase in the diffusion coefficient of water vapor. Thus, reduction in pore area offsets increased diffusivity at altitude, and water vapor loss through the eggshell at any altitude remains the same as at sea level. The data suggest a structural adaptation of the shell to altered diffusivity of gases at altitude in order to prevent excessive water loss of eggs during natural incubation.
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