Biomedical subjects

B Bima

Publications and source records attributed to B Bima.

2 recordsLinked to original sources

PubMed1976

Isoniazid acetylator status of Black South African tuberculosis patients.

Black male tuberculosis patients (106) were phenotyped into 59% fast and 41% slow acetylators with isoniazid (NH) plasma half-lives. The antimode time dividing the two acetylator groups was longer than that previously reported for Whites. The therapeutic significance of INH acetylator phenotyping per se is questioned since it provides neither a measurement of the amount of INH absorption nor of its distribution within the body.

Acetylation↗

PubMed1975

A preliminary report on cephradine.

Plasma cephradine levels were measured after parenteral and oral administration to healthy adults. Plasma cephradine contrations of 7 - 15 mug/ml were measured after 0.5 g had been administered by mouth, and concentrations of 12 - 57 mug/ml were measured after parenteral administration; they fell to 3 mug/ml within 240 minutes except after intramuscular administration. The results of an open clinical trial conducted among 10 patients suffering from urinary tract infections were satisfactory.

Administration, Oral↗