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Biomedical subjects

B Bonke

Publications and source records attributed to B Bonke.

At least 19 recordsLinked to original sources

Unconscious learning during anaesthesia.

Forty-three surgical patients were, during general anaesthesia, presented (via headphones) with either statements about common facts of some years ago (group A), or new verbal associations, i.e. the names of fictitious, nonfamous people (group B). None had any recall of intra-operative events. In a postoperative test of indirect memory, patients in group A answered more questions about the 'common facts' correctly than those in group B (p < 0.005), which reflects the activation of pre-existing knowledge. Furthermore, patients in group B designated more 'nonfamous names' as famous (thus falsely attributing fame) than patients in group A (p < 0.001), which demonstrates that information-processing during anaesthesia can also take place as unconscious learning.

Adolescent

Implicit memory tested in children during inhalation anaesthesia.

Memory for stimuli presented during inhalation anaesthesia was tested in 80 children undergoing eye surgery. Two groups were exposed, in a random double-blind study, to repeated neutral phrases including either the colour orange or green. A postoperative colouring task was used as a test of implicit memory to detect any preference for the colour named under anaesthesia. No colour preference attributable to implicit memory could be demonstrated. One patient had a distinct preference for the named colour. No patient remembered any intra-operative events.

Anesthesia, Inhalation

Pre-operative anxiety variables as possible predictors of post-operative stay in hospital.

The extent to which measures of pre-operative anxiety predict post-operative hospital stay, over and above what is predicted by biographical, medical status and post-operative anxiety variables, was examined in 81 cholecystectomy patients. Hierarchical multiple regression analysis revealed that patients who were older, had lower health status and suffered from wound infection, had a longer post-operative hospital stay than others. None of the pre-operative anxiety measures had a significant incremental value in the prediction of the post-operative hospital stay.

Anxiety

Failure to demonstrate unconscious perception during balanced anaesthesia by postoperative motor response.

Eighty patients undergoing a standardized balanced anaesthesia were randomly assigned to either a suggestion group (N = 38) or a control group (N = 42), in a double-blind design. Anaesthesia was maintained with nitrous oxide, enflurane and fentanyl. Patients in the suggestion group were played seaside sounds, interrupted by statements of the importance of touching the ear during a postoperative visit, by means of a prerecorded audiotape and headphones. Tapes containing these suggestions were played from 30 min after the first incision, for a duration of 15 min. Patients in the control group were only played seaside sounds. There were no significant differences between the groups in either the number of patients touching their ears postoperatively or the number and duration of ear touches.

Adult

Preoperative anxiety and motives for surgery.

Preoperative anxiety was assessed in 20 patients undergoing surgery for esthetic reasons and 20 other surgical patients. Patients with plastic surgery reported significantly less anxiety than patients with general surgery, as measured by the State-Trait Anxiety Inventory.

Adult

Shortening the State-Trait Anxiety Inventory.

Questionnaires that are used in studies with severely patients should be as short as possible. Abridged versions of existing inventories are very practical in these instances. The answers of 444 subjects in three samples (cancer patients, medical students, surgical patients) were used to investigate the possibility of constructing short and reliable versions of the scales of the State and Trait Anxiety Inventory. A stepwise regression procedure showed the possibility to reliably predict the total score of the unabridged versions by means of weighted sums of eight items for each scale. Omission of weights did not lead to substantial loss of information. Cronbach's alpha of the State-scale decreased from 0.93 to about 0.85 for different combinations of items and from 0.91 to about 0.82 for combinations of eight items of the Trait-scale. The relationship between both scales was only slightly modified by the shortening procedure.

Adolescent

Detection of lacunar infarction in brain CT-scans: no evidence of bias from accompanying patient information.

Interobserver agreement in assessing brain CT-scans is, in general, high. The extent, however, to which such agreement is caused by bias through knowledge of other clinical details remains uncertain. The hypothesis that observers are somehow prejudiced before assessing ambiguous CT-scans in this particular situation was tested. Sixteen neurologists and 16 radiologists volunteered to interpret two ambiguous brain CT-scans, with regard to the presence or absence of a lacunar infarct in the region of the internal capsule. The scans were accompanied by "patient" information that was or was not suggestive of a stroke. These scans were camouflaged by a variety of other scans, to be assessed in the same way, to mask the purpose of the study. It was assumed that the observers, in their assessments of the scans, would somehow let their ratings of the likelihood of a lacunar infarction in or near the internal capsule be subject to the accompanying information. Results showed lower ratings produced by neurologists (i.e., less likelihood of an infarction) than by radiologists in the majority of all assessments, but no bias by the accompanying information.

Cerebral Infarction

Auditory perception during general anesthesia: psychologic consequences.

Since the introduction of general anesthesia in the middle of the 19th century, incidents of auditory perception during general anesthesia have been reported in the medical literature. Most of these reports have dealt with purely medical issues, and surprisingly little has been written on the psychologic sequelae of these instances of auditory perception. We discuss the possible psychologic consequences of such perception, and suggest methods of treatment and prevention of the negative aspects of auditory perception during general anesthesia.

Aged

Effects of sounds presented during general anaesthesia on postoperative course.

In a double-blind, randomized study, patients undergoing cholecystectomy were administered one of four different sounds during general anaesthesia: positive suggestions, nonsense suggestions, seaside sounds or sounds from the operating theatre. The effect of these sounds on the postoperative course was examined to assess intraoperative auditory registration. No differences were found between the four groups in postoperative variables.

Adult

The stability of the A-Trait subscale of the STAI for stress and passage of time.

One hundred and eighty-eight surgical patients completed the A-Trait subscale of a Dutch version of the State-Trait Anxiety Inventory (STAI-DY) on the day before the operation and again 3 days later. A-Trait total-scores were significantly lower in the second measurement (p less than .01), and weighted kappa techniques showed disagreement in 8 of 20 pre-postsurgery items. Nine to 12 months postsurgery, 90 patients completed the measure again. Total-scores in session 3 were significantly higher than in session 2 (p less than .02), and 15 items showed disagreement between both sessions, with more agreement in Anxiety-present than in Anxiety-absent items. The ranges of the A-Trait score-changes between the different sessions turned out to be rather wide. These results indicate some instability of the A-Trait subscale of the STAI and argue for a cautious interpretation of individual scores.

Adolescent