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Biomedical subjects

B Bourrit

Publications and source records attributed to B Bourrit.

10 recordsLinked to original sources
PubMed1987

[Treatment of male sterility by in vitro fertilization].

A pregnancy obtained through in vitro fertilization in a case of male sterility due to oligospermia with high FSH is reported. After a review of controlled studies dealing with classical andrological treatments (repair of varicocele, treatment of prostatitis and immunological sterility), the place of in vitro fertilization is evaluated in relation to intrauterine insemination using active sperm.

Adult↗
PubMed1985

Mating is random.

Human leukocyte antigen (HLA) typing was undertaken in 151 unrelated blood donors and in 35 normal couples having at least two living children. We compared observed and expected sharing of HLA antigens at four loci in normal couples. We also compared the observed sharing in couples with the expected sharing in unrelated blood donors if taken two by two and with the sharing observed after 1000 "synthetic matings" of normal couples. No statistically significant difference in HLA sharing appeared between these groups. Furthermore no differences were observed in the probabilities of sharing individual HLA antigens among the different groups. We thus conclude that the observed HLA sharing in normal couples is governed by chance alone and that mating is random in our population.

Female↗
PubMed1985

[Reproduction and immune factors in the male].

Sperm antigenicity is demonstrated by the formation of sperm antibodies following vasectomy and by the possible occurrence of hypersensitivity reactions in women to seminal fluid. It may be that immunosuppressor factors in seminal plasma, as well as certain placental hormones, could explain the fact that sperm are not rejected immunologically in the female genital tract. The role of these different immune factors in male infertility and in the pathogenesis of AIDS is discussed.

Acquired Immunodeficiency Syndrome↗
PubMed1985

[Reproduction and immune factors in women. Pregnancy, habitual abortion and HLA histocompatibility].

Immune tolerance of the mother towards the fetus, which is like an allograft, may be explained partially by the presence of immunosupressor factors produced by the placenta. The maternal production of antibodies against trophoblastic antigens would seem equally necessary to prevent the fetus being rejected by cytotoxic maternal lymphocytes. Where there is marked histocompatibility between partners the protecting antibodies are absent and that gives rise to repeated abortions. This hypothesis is discussed as well as the rationale of treatments that are aimed at increasing maternal production of protective antibodies in cases of habitual abortion.

Abortion, Habitual↗
PubMed1979

[Maturation of the cervix by prostaglandins before inducing termination of pregnancy, in the first trimester (author's transl)].

A new technique for instilling the gel of PGF2 alpha into the endocervix is presented. The study is concerned with 100 therapeutic terminations of pregnancy by dilatation and suction carried out in the first trimester of pregnancy. The efficacy of PGF2 alpha gel is compared with that for tablets of PGE2 and a placebo group. Softening of the cervix was evaluated using a tocodynamometer. PFG2 alpha gel often gives remarkable results, but the response to treatment is unpredictable. Secondary effects, and in particular digestive effects, occur frequently but are always easily controlled.

Abortion, Induced↗
PubMedDate not supplied

The value of the postcoital test according to etiology and outcome on infertility.

Post coital test (PCT) has been analysed in 150 women divided into 3 groups of 50 patients consulting for infertility. In group I, women achieved pregnancy whereas in group II, women were not pregnant during the same period of observation and had a sterility of non-tubal origin. Group II included women with infertility due to tubal factor. The results of the PCT were not significantly different in group I and in group III. More than 50% of the women had a good PCT (more than 7 motile sperms/hpf). In women of group II, 75% had an inconclusive test (less that 5 sperms/hpf) or negative tests, significantly different from the % observed in group I (44%). Inconclusive PCT in group II were due to anovulatory cycles in 50% of the cases and to cervical infection in 25% of the cases. Status post-cauterization of the cervix, anatomical or immunological problems and sexual dysfunctions accounted for the remaining cases. Prognostic significance of the PCT is discussed according to these results.

Cervix Mucus↗