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Biomedical subjects

B Bozhkov

Publications and source records attributed to B Bozhkov.

At least 37 records · Page 2Linked to original sources

[Levels of immunoreactive insulin in laser irradiated rats].

The authors described the results from a study on immonoreactive insuline in rats after their irradiation in the region of the pancreas with rubine laser with beam energy of 0, 13 Joul/impulse. The irradiation was made singly with 7--10 impulses. The level of immunoreactive insulin was raised to 33,83 microliter I/ml in nonirradiated rats and to 48 microliter/ml per 24 hours after irradiation and reached its maximum of 54 microliter/ml after 48 hours of its irradiation, but then returned to its normal values after 72 hours. The same elevation of insulin was found also in rats, irradiated in the region of liver, kidney and heart. The discovered histomorphologic findings in the tissues after irradiation revealed activation of mesenchyme, interpreted as a reaction of dystrophic changes, caused by laser beams. The elevation of insuline was connected with changes in hypophysial-adrenal system, presenting the type of the general adaptation syndrome, and, on the second place, site of the realesed mediators (sympathycomymetics) in this stress reaction.

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[Development of delayed hypersensitivity in rats with streptococcal myocarditis and arthritis].

The authors induced streptococcal myocarditis and arthritis in rats by means of three methods. They proved the development of late hypersensitivity in the experimental animals by determining skin sensitivity and by transfer of lymphocytes and leucocytes from animals with myocarditis and arthritis of healthy recipients. The maximal percentage of animals with late hypersensitivity was obtained in the groups, in whom leucocytes from rats with arthritis were transfered. The arthritis was caused by administration of alive streptococcal culture (at 14 days intervals) three times. Recipients of leucocytes from rats with adjuvant arthritis and streptococci were next. The smallest percentage of successful transfer of late hypersensitivity was obtained in recipients of leucocytes, isolated from animals with streptococcal arthritis and myocarditis, induced after single contamination with alive streptococcal culture.

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