Biomedical subjects
Publications and source records attributed to B Brodie.
Care of the insane during the 17th and 18th centuries was undeniably grim until the advent of moral therapy. Wasserbauer and Brodie explore the humanistic approach that laid the groundwork for early psychiatric nursing.
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The task of providing infants adequate amounts of nutritious milk, in spite of mothers' ability to produce breast milk, has never been easy. In America cow's milk became the food of choice when mothers ceased to breast-feed their infants. In the mid-1800s advances in bacteriology and chemistry led to a beginning understanding of the role of microbes in food and the development of commercial proprietary formulas. Many mothers discontinued breast-feeding at an early age and relied on these products for their children. With the growth of cities, dairy farms were pushed many miles from the consumers of milk. The distance the new uncooled milk had to be transported, especially during the hot summer months, increased the chances of milk-borne diseases infecting infants. To combat the high rates of infant gastroenteritis and death, welfare reformers and health professionals banded together to improve the milk supply through pasteurization, certification, and safe distribution; and to educate the public, especially mothers, on ways to feed and keep their infants healthy. Through their close contact with mothers in their homes, nurses taught these women how to prepare, store, and feed infants' milk. When their babies survived the summer, mothers developed a sense of trust in the nurse and the things she taught about ways to protect their infants and the entire family's health.
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We assessed risk factors for human immunodeficiency virus (HIV) infection in 633 heterosexual intravenous drug users. The HIV seroprevalence was 26% in blacks, 10% in Hispanics, and 6% in whites. Intravenous cocaine use significantly increased the risk of HIV infection, with a seroprevalence of 35% in daily cocaine users (odds ratio, 6.4; 95% confidence interval, 3.0 to 13.3). Black subjects were more likely to use cocaine regularly. Drug use in shooting galleries and sharing of drug injection equipment were also associated with HIV infection and were more common in cocaine users. By multivariate analysis, black race, daily cocaine injection by blacks and Hispanics, all other cocaine injection, heavy use prior to entry into methadone treatment by blacks, and use of drugs in shooting galleries were independent predictors of HIV infection. Methadone therapy was associated with substantial reductions in heroin use and some reduction in cocaine use, but 24% of cocaine users receiving methadone began or increased cocaine injection after entry into treatment.
The development of clinical specialists is traced from the beginning of the profession into the present. Nurse anesthetists were the first clinical specialists to appear in the 1880s. In the 1900s, public health nurses began to specialize as infant, school, industrial, and tuberculosis nurses and midwives. From the 1950s to the present, the growth of critical care specialists paralleled the extraordinary growth of medicine. Underlying all specialization has been nursing's commitment to provide needed care.
Blood from 171 pregnant and 65 nonpregnant cows was taken at slaughter for culture and examined during the culturing period for Trypanosoma theileri once a week for 5 weeks. Of the 171 fetuses from the pregnant cows, 119 (69.6%) were greater than or equal to 4 months gestation; blood samples from these fetuses were also taken for culture. Of 236 cows (81 of 171 [47.4%] pregnant and 20 of 65 [30.8%] nonpregnant cows), 101 (42.8%) were culture positive. More of the pregnant than nonpregnant cows were culture positive (P less than 0.05). More beef cows (48.0%) than dairy cows (34.1%) were culture positive (P less than 0.025). Two of the 119 (1.7%) fetus samples were found culture positive. The percentages of positive cultures from Brucella-reactor cows, 18 of 40 (45.0%), and from non-Brucella-reactor cows, 83 of 196 (42.3%), were similar. However, both of the culture-positive fetuses were from Brucella-reactor cows.
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The physiologic correlates of ejection sounds have been studied by simultaneous phonocardiograms, echocardiograms and high fidelity pressure tracings. Ejection sounds associated with semilunar valve stenosis or hypertension of the systemic or pulmonary circulation occur at the moment of complete opening of the aortic or pulmonary valve recorded echocardiographically. The start of opening of these valves occurs at the onset of the pressure rise in the corresponding great vessel and completion of valve opening always occurs on the pressure upstroke. The ejection sound in the presence of stenotic valves occurs with checking of the opening motion of the thickened valve cusps. Although the hypertensive ejection sounds also occur at the precise moment of full opening of the valve it remains to be seen whether this relationship is causal or coincidental.
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