Oral-gastric lavage is an important tool in the management of oral toxic ingestions. An unusual complication of the impaction of the oral-gastric tube in the esophagus is described. This is the first report of the use of flexible endoscopy in the management of the complication.

Adolescent↗

PubMed1985

Cytomegalovirus esophagogastritis in a patient with acquired immunodeficiency syndrome.

Symptomatic cytomegalovirus involvement of the gastrointestinal tract has become increasingly recognized in patients with acquired immunodeficiency syndrome. This may take varying forms, often mimicking more well known entities. This is a report of a male intravenous drug abuser with documented acquired immunodeficiency syndrome, who developed dysphagia and evidence of distal esophagitis. Although this was initially thought to be related to reflux peptic disease, he subsequently was documented to have cytomegalovirus esophagitis and gastritis. His course was further complicated by small bowel perforation with cytomegalovirus found here as well. Cytomegalovirus infection, in general, and its increasingly recognized role in the morbidity of patients with acquired immunodeficiency syndrome, is discussed.

Acquired Immunodeficiency Syndrome↗

PubMed1984

Patterns in effects of sulfhydryl reagents on transport in bovine lens.

Active fluxes of Na+ and Rb+ and mediated transport of organic nutrients in the bovine lens were inhibited by five sulfhydryl reagents, whereas that of inorganic ions was increased, with the exception of the ouabain-resistant component of Na+, which was not significantly altered. The changes produced by the reagents indicate that cysteinyl residues are essential for normal operation of most of the transport systems investigated. The variable effectiveness of the reagents on transport of some of the solutes may provide information on the microenvironment of critical sulfhydryl residues in the transporters: that for glucose, adenosine, and influx of Ca++ appears to be hydrophobic; for acetate and influx of Na+, hydrophilic. Comparison of the rates of inactivation of influx via the L-system of 1-aminocyclopentane-1-carboxylate indicates that p-chloromercuriphenylsulfonate is most effective, inhibiting almost completely in 10 minutes. There was no significant lag in inhibition by the selective glutathione oxidants, tert-butylhydroperoxide and diazinedicarboxylic acid-bis (N,N-dimethylamide), indicating that they either rapidly oxidize glutathione in superficial cellular elements, or, less probably, act directly on the transporter.

Animals↗