Biomedical subjects

B Calciu

Publications and source records attributed to B Calciu.

12 recordsLinked to original sources

PubMedDate not supplied

[The risk of tuberculosis in students of professional schools].

In four technical schools in a Burcharest district, the first grade scholars were tested at the beginning of the term with 2 units PPD; those with a reaction of 0--9 mm received BCG vaccine. After 6 months, in the 3rd term, they were controlled by MMR examination which was repeated in the second year. The incidence of tuberculosis detected by X-ray and clinically was of 298.8 per 100 000 in the frist year and 283.6 per 100000 in the second year. In all disease cases but one the intradermoreation and greater than or equal to 15 mm which may thus be considered the risk group (a risk of 9.5 per thousand); there were no cases among the children revaccinated with BCG. In conclusion it is recommended to apply in adolescent communities tuberculin testing and BCG revaccination of the non-infected children 0--9 mm) in their first term and periodical X-ray control of the risk group, i.e. those with a reaction of 15 mm or more.

Adolescent↗

PubMedDate not supplied

[The risk of tuberculosis infection and disease among children in contact with tuberculous foci].

Three groups of children aged 0-14 years, in the 4-th district of Bucharest, have been followed up during 1988-89, as follows: a retrospective group--331 contact children in new tb foci registered in 1986-87; a prospective group--213 contact children in newly registered foci in 1988 and a group of 49 contact children in chronic foci. The children have been controlled clinically and X-ray and tuberculin tested on case-finding of the index-case and 3, 6 and 12 months thereafter; those from the retrospective group even after 2-3 years. The non-infected children were BCG vaccinated; in those infected chemoprophylaxis was administrated. The most dangerous infection sources for children were the tb bacilli eliminators on microscopy. The tuberculin conversions were noted during the first 3-6 months after contact; the children from chronic foci can converse even after 1-3 years. The active tuberculosis in children were noted on the initial check-up and were missing during the follow-up period, even in chronic foci. These observations could be accounted to the prophylactic measures applied in contact children, corroborated with intensive treatment of infection sources. Since most of disease cases in children were under 2-3 years of age, we consider necessary to continue the BCG vaccination at birth.

Adolescent↗

PubMedDate not supplied

[Epidemic of tuberculosis in a maternity hospital triggered by congenital tuberculosis in a newborn infant].

The development of several cases of miliary tuberculosis in infants aged 3--4 months, born in the same maternity led to an epidemiological investigation. On this occasion it was discovered that one of the patients that had been discharged immediately after delivery had pulmonary granulia a monthlater. The immature newborn was left in the maternity and died after one month with a diagnosis of "pulmonary microabscesses". The histopathologic examination of the lungs showed the presence of necrotic foci without any cellular reaction. Five months after the death of the infant a new examination of a pulmonary fragment was performed and Ziehl-Neelsen staining evidenced a large number of acido-resistant bacilli filling the lung alveoles. It was shown in this way that the infant with tuberculosis was the primary source of infection. All the 8 children that had developed the disease had been hospitalized in the same ward with the sick child. The transmission of the bacilli was done indirectly, through the feeding tubes that had not been sufficiently serilised, and the penetration ronte was the digestive tract. In two cases an otic primary focus was discovered and in one case an intestinal one was found on necropsy.

Cross Infection↗

PubMedDate not supplied