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Biomedical subjects

B Calcraft

Publications and source records attributed to B Calcraft.

15 recordsLinked to original sources

Patient's assessment of an information booklet on Crohn's disease written by a patient.

Patients with Crohn's disease want information about the condition. "So you've got Crohn's disease", an information booklet written by a patient was sent to patients for evaluation. Most found it useful, particularly in the practical advice, and suitable for all patients with Crohn's disease. Patients can be a valuable source of information for other patients and doctors. They should be encouraged to share their experiences.

Attitude↗

A study of the menopause, smoking, and contraception in women with Crohn's disease.

One hundred and ninety-six women with Crohn's disease from south-east Wales were asked to provide details of their menstrual cycles, age at menopause, history of surgery, smoking habits and use of oral contraceptives. One hundred and forty-six provided the information (response rate 77 per cent). Eighty-four were still menstruating, three were pregnant, 10 had undergone hysterectomy, one had a pharmacologically-induced menopause and 48 had had a physiological menopause. Of these 48 women, 33 were diagnosed as having Crohn's disease before the menopause. Twenty-five of these were smokers. The mean age at menopause was similar in smokers and non-smokers and in those diagnosed before and after the menopause. The mean age at menopause was between 46 and 47. A logistic analysis using the 'status quo' method showed that 50 per cent of women with Crohn's disease had the menopause at 47.6 years compared with 49.6 years in a group of healthy women from the same area. The two groups had similar smoking habits and it would seem that a premature menopause is associated with Crohn's disease.

Adult↗

Crohn's disease in Jewish people--an epidemiological study in south-east Wales.

The prevalence of Crohn's disease in the Jewish population of south-east Wales was established by a postal survey, review of case notes and a survey of Jewish congregations in the three synagogues of the area. The prevalence of Crohn's disease had been established in various earlier studies at 52/10(5). Seven Jewish patients were identified amongst a population of between 1,750 and 2,500. The prevalence ranged from 280 to 400/10(5) (95% confidence interval 120-862/10(5]. There was no significant difference in prevalence between orthodox and reformed Jews. Jewish people are at a relative risk of developing Crohn's disease of 5.4-7.7 (95% confidence interval 2.3-17.2, p less than 0.001), but the role of diet is yet to be established.

Adult↗

Employment after myocardial infarction amongst previously healthy men.

A postal questionnaire was sent to 55 men 18 months after their first myocardial infarction; information obtained was supplemented by interview with two of the authors (PW and GC). Fifty-three men had been in full-time employment prior to their illness, 38 of them in manual work. Their return to work and changes in employment were examined and, in addition, enquiries were made about subsequent health, assistance from trade unions and the local Disabled Resettlement Officer (DRO). Details of attitude to subsequent physical exercise and sexual activity were also recorded. Eighteen months after myocardial infarction, only 35% of these men were employed and 27% asymptomatic. Patients in heavy manual work were largely unable to return to their previous job and little assistance was obtained from trade unions. Even when patients were made aware of the existence of the DRO, few approached him for advice. A counselling service is needed for patients recovering from an infarct to encourage them to return to an active and profitable life.

Counseling↗

An audit of a medical anticoagulant clinic in a District General Hospital.

The working and costs of the anticoagulant clinic at the Royal Gwent Hospital was reviewed over the period July 1980-June 1981. The hospital notes of the patients were reviewed and a questionnaire distributed to each patient. The majority of patients have cardiac valve problems or deep vein thrombosis, the latter sometimes being associated with pulmonary emboli. No major complications were reported during the year, but 9.7% reported rectal bleeding or haematuria. The annual cost of running the clinic is approximately 20,000 pounds and, if this is representative of Britain as a whole, about 3.75 million pounds is spent annually on anti-coagulation clinics. Several recommendations are made for improving the anticoagulant clinic service, which includes making sure that the doctor at the clinic and the patient are made aware of the reason for anticoagulation, its duration, and possible side effects and interactions with other drugs.

Anticoagulants↗

Persistent asthma after treatment with beta-blocking agents.

Two atopic subjects with previously trivial asthma developed severe wheezing after receiving beta-adrenergic blocking agents. These drugs were discontinued but severe airways obstruction was still present more than 18 months later.

Adrenergic beta-Antagonists↗

Psychiatric disorder and outcome in irritable bowel syndrome.

A link between irritable bowel syndrome (IBS) and psychiatric illness is well recognized. The authors set out to establish whether a group with a risk of poor outcome IBS could be identified at presentation to a general hospital clinic in a prospective series of 70 subjects. Potential risk factors showed no correlation with IBS outcome at 6-9 months. There was a high rate of persistent mental illness. Clinicians offering specialist care for IBS should consult with psychiatric services to provide assessment irrespective of IBS outcome if major psychopathology is not to be neglected.

Adolescent↗