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Biomedical subjects

B Cappuccini

Publications and source records attributed to B Cappuccini.

10 recordsLinked to original sources

Rubella in Umbria (Italy): serological assessment of immunity in adult women and congenital rubella detection after 1978.

Antibody to rubella virus was measured in 3655 serum samples collected during 1973-1979 from females of child bearing age in Umbria (Italy). The overall incidence of seronegatives was 24 percent (hemagglutination inhibition (HAI) antibody less than 1:16), with a higher proportion of seronegatives in the first years studied (1973-1976). A history of rubella infection was shown to be an unreliable index of immunity. One case of rubella congenital syndrome was detected following laboratory screening of newborn babies after the rubella virus circulation in Umbria during 1978. The persistence of a risk associated with rubella virus in women living in Umbria indicates the importance and the urgency of the adoption of a full-scale rubella control campaign.

Adolescent↗

[Serological studies of the immunological condition versus rebulla virus in maternal and neonatal serum samples].

In 116 serum pairs sampled from the mother and the newborn at delivery, the antibody level against Rubeola virus has been assessed haemagglutination inhibition test. Thirty one per cent of the mothers resulted not protected, as the antibody titer was below 1/16. A situation akin to that described in the same percentage of not protected women was 29,45%. In 19% of the newborns the antibody level against the virus proved higher than the mother's one by at least two dilution factors. Research work is in progress to try the reason of this result, as a possible consequence of different Ig classes or aspecific inhibitors involved.

Adult↗

[Poland's syndrome: presentation of two cases diagnosed during the neonatal period (author's transl)].

Two cases of Poland syndrome, diagnosed during the neonatal period, are reported. The children exhibited the following malformations: absence of the costosternal head of the pectoralis major, brachysyndactyly, hypoplasia of the upper limb. There were also other associated anomalies such as: Sprengel deformity in one case, hypoplasia of the lower limb and absence of a toe on the same site, in the other case. The authors point out the possibility of associating other multiple abnormalities and they examine the various pathogenic hypothesis presented in the literature.

Ear↗

[Amniotic band syndrome (author's transl)].

The authors present a critical revision of the literature concerning the pathogenic hypotheses and the opinions, during the centuries, about the origin of the deformities caused by amniotic bands. Here they describe two cases of severe deformities caused by amniotic bands which can be classified in types I and V according to Onnipoff and Hall. In the first case the newborn died immediately after the birth: the other one lives in good health after multiple surgical operations. In accordance with the anatomical reports that were found using very specific techniques and methods, the authors are inclined to accept Torpin's hypothesis, which affirms that the initial moment of the series of events which causes the formation of the amniotic bands is the breakage of the amniotic sac.

Abnormalities, Multiple↗