Biomedical subjects

B Carme

Publications and source records attributed to B Carme.

149 records · Page 9Linked to original sources

PubMedDate not supplied

[Retrospective study of mortality in children less than 5 years old in a rural area of the Brazzaville region (People's Republic of Congo). II. Analysis of birth conditions].

An analysis of the circumstances surrounding the birth of 1,003 children (976 deliveries) born in 1976 in Linzolo , a rural village in the People's Republic of the Congo, led to the identification of certain socio-demographic conditions related to the mothers, the analysis of delivery-related conditions and the establishment of a normal curve for birth weight. This same cohort had been the object of a longitudinal study in 1981 on the causes of mortality before the age of 5 years.

Adult↗

PubMedDate not supplied

[Prevalence of human filariasis with microfilaremia in Gabon].

Direct examinations of blood and serologic tests were used to assess the intensity of the filarial endemicity in Gabon. Both methods revealed that the prevalence of filariasis with microfilaremia (Loa loa and Dipetalonema perstans) is presently very elevated. The areas that are more involved are the forest regions as well as the highest ones (ogoue, Lolo, Ngounie). Women appeared to be suffering from loasis to a lesser extent than men. On the other hand, the prevalence was identical for Dipetalonema perstans. For the gabonese population one can approximately say that 3 out of 5 adults patients have filariasis, two being D. perstans and one L. loa. Consequently these affections represent a major public health problem. Finally one must note that no case of lymphatic filariasis has been identified.

Adult↗

PubMedDate not supplied

[Results of a systematic study of drepanocytosis in 1,500 Gabonese using hemoglobin electrophoresis].

Hemoglobin electrophoresis realised as a routine screening test on 1 500 gabonese individuals revealed the existence of a sickle cell abnormality n 24.40% cases (22.27% were AS heterozygotous and 2.1% were SS homozygotous). Bapounov and Fang ethnies appeared to be the most involved. The importance of such disturbance (I gabonese individual out of 4 is concerned) could justify the creation of Prenatal Counseling Centers mainly dealing with this genetic problem.

Adolescent↗

PubMedDate not supplied

[Drug sensitivity of Plasmodium falciparum in vivo and in vitro in Brazzaville (Congo)].

Various projects were launched in 1993 to monitor the chemosensitivity of Plasmodium falciparum in Congo. Resistance of 34 strains in Brazzaville to chloroquine, quinine and mefloquine and of 35 to halofantrine was investigated in an in vitro survey using an isotopic micro test. The resistance rates were 61.8, 14.7, 3.0 and 0.0% respectively. Thus, the chemoresistance which first appeared in 1990 is confirmed and is stable in the population. This finding was further confirmed by a parallel in vitro analysis of sensitivity to chloroquine in Brazzaville. A chloroquine monitoring network is now being established throughout the country based on simplified WHO tests of 100 asymptomatic schoolchildren conducted every six months. The first results in 1993, from three Southern regions indicate that parasites are found in 20 to 60% of cases seven days after a standard 3 day treatment with 25 mg/kg, according to the region. The results of in vitro and in vivo tests are very variable. Indeed, the value of such results for these tests for national monitoring is questionable: a more reliable system of identifying true therapeutic failures would be better suited.

Animals↗

PubMedDate not supplied

[Entomophthoramycosis: a case report of a Congolese child with rapid regression using ketoconazole].

We report the second Congolese case of subcutaneous entomophthoramycasis, a rare tropical disease expressed as cellulitis. Despite characteristic clinical features, the diagnosis for this twelve-year old child was confirmed four years after the beginning of the disease. Dramatic clinical improvement was observed within the first month of treatment with ketoconazole.

Antifungal Agents↗