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B Cléro

Publications and source records attributed to B Cléro.

5 recordsLinked to original sources

[Acute bilateral parotitis. Isolated prodrome to anaphylactoid shock following injection of iodinated contrast media].

We report a peculiar case of radiocontrast induced anaphylactoid shock following an intravenous pyelography, which was announced by an hyperacute bilateral parotid enlargement as the sole prodrome. From a review of the literature, two clinical presentation of iodide-induced sialadenitis are individualized according to their pathogenesis. In patients with normally functioning kidneys, the occurrence of a sialadenitis after a short delay (5 minutes to 24 hours) evokes an anaphylactoid mechanism. In patients with renal function impairment, the role played by extrarenal excretory pathways of iodinated compounds and especially the salivary glands, results in a delayed onset (1 to 5 days) of the sialadenitis due to an effect of toxicity.

Acute Disease↗

[Fatal pulmonary leukoagglutination after administration of fresh frozen plasma].

A case is reported of a 73 year old female patient who died during surgery for enlarged nephrectomy as a result of a massive non-cardiogenic pulmonary oedema. She had been given 2 red cell concentrates (450 g) and 3 fresh frozen plasma units (900 g). A postmortem examination did not reveal any pulmonary embolus, acute myocardial infarct, haemorrhage or cardiac tamponade. Further tests on the sera of the 5 plasma donors revealed a neutrophil-specific anti-NA2 antibody. Alveolar leukostasis was confirmed on the postmortem lung slices. This type of transfusion accident occurs for about 1 in 5,000 units transfused, fortunately not all as serious. This case confirms once more that fresh frozen plasma is not the ideal treatment for acute hypovolaemia, 4% human albumin being safer.

Aged↗