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Biomedical subjects

B Collett

Publications and source records attributed to B Collett.

2 recordsLinked to original sources

Evaluation of the use of visual analogue scale in Chinese patients.

The linear analogue score can be used in Chinese patients with relative accuracy provided it has been well explained. The error from employing a vertical presentation is significantly less than that from a horizontal one. The choice of upward or downward orientation is a matter of convenience. Younger patients and those with higher intelligence are quicker to understand the concept and can make better judgement in placing a mark where they wish it to be. A linear analogue scale seems to be a suitable method to record and study pain in a Chinese population.

Adolescent↗

Pathways to complement activation during cardiopulmonary bypass.

Complement activation was assessed in 34 patients undergoing cardiopulmonary bypass. Arterial concentrations of complement fragments Ba and C3d rose in all patients, the increase in Ba preceding that of C3d. At the same time as complement fragments were being generated the arterial neutrophil count fell. These findings suggest (a) that complement activation is initiated by the alternative pathway during cardiopulmonary bypass and (b) that complement activation mediates loss of neutrophils during bypass. Complement mediated loss of neutrophils during the analogous setting of haemodialysis is the result of leucosequestration in the pulmonary vasculature. During cardiopulmonary bypass the lungs are out of circuit, so that activated leucocytes may sequester in other target organs. This may be an aetiological factor in the multi-organ failure occasionally seen after uneventful cardiopulmonary bypass.

Adult↗