PubMed Health⌕ Search

Biomedical subjects

B Cornblatt

Publications and source records attributed to B Cornblatt.

27 records · Page 2Linked to original sources

Electrodermal recovery data on children of schizophrenic parents.

Half-amplitude recovery of electodermal responses is compared in children of schizophrenic parents (high-risk subjects) and children of depressed or normal parents. The results are dissimilar to those reported by Mednick and colleagues on a Danish high-risk sample. No significant differences emerged among the three groups in our study. Recovery did not differ according to sex or severity of illness of the schizophrenic parent. Recoveries of high-risk subjects separated from their homes were not shorter than recoveries of subjects who remained home. Recovery time recorded in childhood was unrelated to global adjustment in adolescence.

Adolescent↗

Biobehavioral risk factors in children of schizophrenic parents.

Research on risk factors for schizophrenia is reviewed with emphasis on children of schizophrenic parents. As children of schizophrenic parents are not representative of the majority of individuals who become schizophrenic, examination of variables such as those relating to home environment or parental characteristics in these children is not expected to contribute greatly to an understanding of risk for schizophrenia or to the search for early indicators of a genetic liability, whereas study of selected biobehavioral variables may do so. Four areas of biobehavioral functioning that have been examined in high-risk research are discussed. Three of these are considered to be compatible with the hypothesis of a neurointegrative defect underlying schizophrenia-proneness and to be promising for further research.

Adolescent↗

Auditory recognition memory in adolescents at risk for schizophrenia: report on a verbal continuous recognition task.

As part of the New York High-Risk Project and in the context of a third round of testing, auditory short-term recognition memory for words and for consonant-vowel-consonant trigrams was measured in normal control adolescents (n = 53) and in adolescents at high risk for schizophrenia (n = 46). Differences in performance between the two groups are attributable to a lower initial memory strength on the part of the high-risk subjects, with trigrams showing larger differences than words. A subgroup of the high-risk subjects characterized by "clinical deviancy" showed, in addition, a (nonsignificant) increase in the rate of information loss from memory for trigrams.

Adolescent↗

Sustained attention in combat-related posttraumatic stress disorder.

There is substantial evidence that PTSD patients have information processing abnormalities for stimuli that are highly relevant to the traumas they have endured. The goal of the present study was to examine whether this extends to neutral stimuli as well. Twenty-four male Vietnam combat veterans with PTSD were compared to fifteen normal male comparison subjects on their performance on a sensitive measure of sustained attention, the Continuous Performance Test-Identical Pairs version (CPT-IP). PTSD subjects did not differ from controls in their ability to discriminate target stimuli from background noise on the CPT. Additionally they performed as well as controls, even in the presence of external distraction. Thus, this study did not find a generalized deficit in attention associated with PTSD on the CPT-IP. Nevertheless, further clarification of the nature of the information processing disturbance in PTSD is warranted.

Adult↗