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Biomedical subjects

B Cylwik

Publications and source records attributed to B Cylwik.

At least 19 recordsLinked to original sources
PubMed1990

[Primary liver cell carcinoma among the population of Białystok in 1975-1988 in relation to hepatitis B virus infection].

In presented study, retrospective epidemiological analysis was performed in 84 patients dead due primary hepatocellular carcinoma, selected from among 17,973 persons dead in Białystok hospitals from 1975 till 1988. In the part from among these patients was estimated prevalence of serological markers of Hepatitis B virus infection, as a potential oncogenic factor. Analysis of this carcinoma diagnosis frequency in particular years showed rising tendency: from 1975 till 1979 number of PHC diagnosis was from 0 to 5 a year, whereas in 1988 it was 13. Percentage of necropsy diagnosed PHC was similar and increased to over 1% of all necropsies in 1988. Mean age of patients dead due PHC was 65, and 71.4% were men. Serological markers of HBV infection were observed in 50% and HBsAg in 34.6% from among PHC-dead patients. These percentage values were significantly higher, than observed in control group of Białystok population, which indicate possibility of association between HBV infection and PHC development.

Adult↗
PubMed1985

Histological and histochemical changes in the dog kidney after renal artery embolization with Spongostan.

Histological and histochemical examinations of canine kidneys 24 hours, 7, 14 and 24 days after embolization of the renal artery with Spongostan showed that during 24 days the resorption and organization of the infarcts in the embolized kidneys and the resorption of Spongostan in the arteries were not yet completed. The intensified reactions to phosphatases, dehydrogenases, and non-specific esterase indicate a prolonged activation of cells playing a role in the resorption and organization of infarcts which may be of significance in the stimulation of immune responses. There were no inflammatory reactions in the embolized arteries.

Animals↗
PubMed1985

[Effect of embolization of the renal artery on histologic changes in primary kidney cancer].

The authors compared the histologic changes in 12 kidneys removed due to renal carcinoma with the changes in 12 other kidneys in which before nephrectomy an embolization of the renal artery with Spongostan had been performed. The results achieved show that the embolization of the renal artery may intensify the lymphocytic macrophagal and fibroplastic interstice of the tumour and according to this may represent a factor which is able to activate the cellular effector mechanism of the antineoplastic immunity of the organism.

Adult↗
PubMed1985

[Microdensitometric research on DNA in the cells of a primary kidney tumor after Spongostan embolization of the renal artery].

In klatsch preparations of renal tumours (light-cellular carcinomas with malignity degree 2 and 3) microdensitometric investigations of the DNA-content were performed. In the 1st group the material came from 10 patients in whom a unique nephrectomy, in the 2nd group from 10 patients in whom 2 days before nephrectomy an embolisation of the renal artery with Spongostan, in the 3rd group from 10 patients in whom 14 days after embolisation the nephrectomy had been performed. From the analysis of the histograms follows that in the cytoblasts of the tumours of the 3rd group the percentage of diploid and paradiploid nuclei is higher than in the groups I and II: deviation to the left of the histogram. However, the index of the mean DNA-content is smaller in the 3rd group than in the 1st and 2nd group, correspondingly: 8.79, 10.52 and 11.8; the difference is statistically significant. The results obtained show that the embolisation of the renal artery may not only lead to a necrosis of the neoplasmatic tissue, but also to an inhibition of the DNA-synthesis in the persisting cancer cells.

Adenocarcinoma↗
PubMed1985

[Chronic pancreatitis as a predisposing factor in the development of pancreatic cancer. Histological and histochemical studies].

The frequency of hyperplasia, squamous metaplasia and dysplasia were examined in glandular tissue from 20 pancreatic specimens resected due to chronic inflammation. Hyperplasia of the epithelium of large pancreatic ducts with formation of papillomatous outgrowths was present in 6 cases. Epithelial hyperplasia of small ducts occurred in 10 cases. Dysplasia and squamous metaplasia of the epithelium of ducts, hypertrophy, hyperplasia and dysplasia of acinar cells were found in 7 cases. In 10 pancreatic specimens hypertrophy and hyperplasia of cells of the islets of Langerhans were noted. Increased histochemical reactions to dehydrogenases and proteinic thiol groups were present in epithelial cells which demonstrated hypertrophy, hyperplasia, metaplasia or dysplasia. Diminution of the PAS reaction to neutral glycoproteins and intensification of the reaction to acid glycoproteins were also noted in the ductal epithelium. The results obtained suggest that chronic inflammation of the pancreas should be clinically regarded as predisposing to the development of pancreatic cancer.

Adult↗
PubMed1976

Effect of clamping of the renal vein in dogs on certain biochemical and histopathological changes.

Experimental investigations were carried out on dogs in which the renal vein was clamped for a period of 15 min, 30, and 60 min consecutively. It has been found that clamping of the renal vein for 15 min results in tissue anoxia and degeneration of the epithelium of the renal tubules. Clamping for 60 min causes cellular acidosis and necrosis of the tubules. It can therefore be said that clamping of the renal vein for even a short time is highly dangerous.

Animals↗