PubMed Health⌕ Search

Biomedical subjects

B Czepulkowski

Publications and source records attributed to B Czepulkowski.

25 records · Page 2Linked to original sources
PubMed1987

Duplication of one of the products of the t(8;21) translocation in a patient with refractory anemia with excess blasts in transformation.

A 34-year-old man with refractory anemia with excess blasts in transformation is reported, having a t(8;21) translocation and a duplication of one of the products, der(21). The duplicated product had not been observed at presentation in malignant disease, as far as we are aware; thus, the findings are discussed with regard to this case and other possible smoldering leukemias. The diagnostic use of cytogenetics is also considered.

Adult↗
PubMed1987

Subtle abnormalities in the short arm of chromosome 11 in acute myeloid leukemia.

A series of four patients with small deletions of the short arm of chromosome #11 is presented. In two of these patients, deletion of 11p was the sole karyotypic abnormality. When compared with similar reported cases an association with FAB type M4 is apparent. Such cases may often be undocumented, because the deletions can be subtle. One patient with erythroleukemia shows an inversion of chromosome #11 involving band 11p15. Because the patients' fetal hemoglobin (HbF) became raised during the course of the disease, it is postulated that the hemoglobin beta chain gene at 11p15 may have been disrupted.

Adolescent↗
PubMed1987

Unusual myeloid leukaemia in patient with Hodgkin's disease.

An unusual case of leukaemia in a patient with Hodgkin's disease is described. The leukaemic blast cell population was typified by the presence of a substantial proportion of binucleate and multinucleate cells, many of which had the morphological features of Sternberg-Reed cells. The circulating and bone marrow blast cells were shown by immunophenotyping to be of myeloid origin.

Hodgkin Disease↗
PubMed1986

Transabdominal chorionic villus sampling.

Transabdominal chorionic villus sampling, carried out with a fine-bore needle and cannula under ultrasound guidance, was as successful as transcervical aspiration but avoided the risks of bacterial contamination associated with the latter technique. The transabdominal procedure can be carried out under local anaesthesia, and multiple samples can be obtained, if necessary, through a single cannula.

Abdomen↗
PubMedDate not supplied

Translocation (9;17) a novel translocation in acute myeloid leukaemia.

We report a case of AML, acute myeloid leukaemia, with a novel translocation involving the short arms of chromosomes 9 and 17. The acute myeloid leukaemia was morphologically classified as FAB subtype M2. A prolonged remission was induced with chemotherapy, followed by a relapse which was associated with the finding of the same translocation.

Aged↗