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Biomedical subjects

B D Ferris

Publications and source records attributed to B D Ferris.

16 recordsLinked to original sources

Radiological study of alignment after total knee replacement. Short radiographs or long radiographs?

The axial alignment on short and long radiographs was measured in 50 knees in 34 patients who had undergone posteriorly stabilised (Insall-Burstein) condylar knee arthroplasty. A mean difference of 1.6 degrees was found when the tibiofemoral angles were compared on short and long radiographs. Short radiographs are probably adequate for routine assessment of knee replacements in a busy out-patient clinic, but for accurate scientific studies the long radiographs are preferable.

Aged

Delayed sciatic nerve palsy following total hip arthroplasty.

Peripheral neuropathy, following total hip arthroplasty, has a reported incidence of 0.7%. However, delayed sciatic nerve palsy has only been reported twice in the literature. We report on two further cases, both of whom developed clinical sciatic nerve palsy at 72 hours after surgery.

Aged

Congenital snapping knee. Habitual anterior subluxation of the tibia in extension.

We describe a rare form of congenital snapping knee. In six knees in four children, the tibia subluxed anteriorly on the femur when the knee was extended and reduced spontaneously on flexion. The abnormal movements were seen and felt as sudden snaps or clunks at about 30 degrees of flexion. All six knees showed similar dysplastic features, although the patients had different clinical syndromes. The mechanism of the subluxation and its management are discussed.

Child

A quantitative study of the tissue reaction and its relationship to debris production from a joint implant.

An attempt has been made to refine the quantitative evaluation of the tissue response to a prosthesis using the goat hip as an experimental model. Total joint replacement was performed in six goats; in three the cup was made of conventional ultrahigh molecular weight polyethylene and in three a new silane cross-linked ultrahigh molecular weight polyethylene was used. The pseudocapsule of the hips was examined histologically at 15, 19 and 24 months following surgery. Small and large polyethylene debris were visualized using semi-crossed polars and were counted. Giant cells were counted after staining with toluidine blue as were macrophages which were identified by dense staining after the acid phosphatase reaction. The amount of small birefringent debris was closely related to the number of macrophages in the pseudocapsule. This method of assessment may be helpful in comparing the tissue reaction of different polymers.

Animals

Morphology of the femur in proximal femoral fractures.

We studied the morphology of the contralateral femur in 10 patients with subcapital fractures, 10 with trochanteric fractures and 10 with unilateral osteoarthritis. We found that the patients with trochanteric fractures had a significantly shorter femoral neck (4.5 +/- 0.5 cm) than patients with subcapital fractures or osteoarthritis (5.4 +/- 0.4 cm). It may be that this difference in femoral neck length is related to the site at which a proximal femoral fracture occurs.

Aged

Axillary aneurysm after shoulder injury. A report of 2 cases.

Two cases of false aneurysm of the axillary artery occurred after closed shoulder injuries. One was a dislocation of the shoulder, and the other was a fracture of the lesser tuberosity. In both cases the diagnosis was delayed, and only became apparent after excessive bruising was seen.

Aged

Brace treatment of Colles' fracture.

Twenty patients with Colles' fractures were treated with a functional brace that allows wrist motion. The result was compared with a similar group of patients treated with a plaster cast. Dorsal displacement of the fracture was less and wrist function was better in the brace group. Swelling of the hand during the early stages was observed in the brace group; and because this may necessitate brace adjustment, increased medical supervision is necessary for this period.

Adult

To stitch or not to stitch the fat?

A total of 22 patients having hip replacements were studied to determine biochemically whether or not fat stitches cause fat necrosis. We found that fat necrosis, as measured by the triglyceride concentration of the drainage fluid, occurred in all wounds. The use of a fat stitch did not increase the amount of fat necrosis, but significantly reduced the amount of fluid drained (P less than 0.001; Student's t test). This retention of triglycerides is probably undesirable as they can act as a substrate for prostaglandin synthesis.

Adipose Tissue

Coracoid process transfer for acromioclavicular dislocations. A report of 20 cases.

Twenty patients with acromioclavicular dislocations treated by transfer of the coracoid process to the clavicle were reviewed and were compared to a previous study. Surgery was performed for acute dislocations in seven cases and for chronic dislocations in 13 cases. At the follow-up examination (5.6 +/- 3.5 years for acute and 4.0 +/- 3.6 years for chronic dislocations), all patients had some relief of their symptoms. Nine patients had residual aching in the joint, and this was associated with an older age at injury (40 years as opposed to 25 years for chronic dislocations). Complications included superficial wound infections in two patients, transient stiffness of the shoulder in two patients, loss of range of movement in one patient, and subjective weakness in one patient. In general, satisfactory results were achieved in younger patients, but as the results of conservative treatment of these injuries are comparable, the operation is indicated only in patients with symptomatic chronic acromioclavicular dislocations.

Acromioclavicular Joint

An unusual presentation of tuberculosis--'injury TB'.

Thirteen patients are presented who developed tuberculosis at the site of injury. They were all immigrants from areas where tuberculosis is endemic. The presence of injury caused a delay in diagnosis and therefore appropriate treatment. In an immigrant with an injury that pursues an unusual or protracted course, tuberculous infection should be considered.

Adolescent

Altered organization of non-collagenous bone matrix in osteoporosis.

In osteoporosis it is postulated that while the amount of bone is diminished, the quality of the bone is unaltered. Recently relatively novel methods of analysis have shown that, at the fracture site of osteoporotic subcapital fractures, there is a marked change in the molecular orientation of components of the non-collagenous bone matrix. These procedures, now applied to iliac crest biopsies, confirm earlier findings of altered orientation of the proteoglycans at the subcapital fracture site but show that very similar changes occur even in the iliac crests from patients with both types of osteoporotic proximal femoral fracture. Thus, whereas the amount of these acidic moieties of the non-collagenous bone matrix was unchanged, the molecular orientation was markedly altered, albeit not to the same extent as that found at the fracture site. These results imply that the quality of the bone, as well as the quantity, may be generally affected in osteoporosis.

Adult