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Biomedical subjects

B D Perchuk

Publications and source records attributed to B D Perchuk.

6 recordsLinked to original sources

[The interrelations and essence of adaptation and disease (apropos the article by V. N. Galankin The interrelationship of adaptation and disease in phylo- and ontogeny)].

The views by I. V. Davydovskiĭ and V. N. Galankin are considered and their similarity is shown. The original opinion of the author is as follows: (1) the adaptation and disease are relatively independent properties of the organism and, thus, are interrelated as parts of the whole; (2) both adaptation and disease are included into the essence of the organism but are not identical to the essence of each other.

Adaptation, Physiological↗

[Preparation of histotopographic goiter sections and endometrium scrapes for relevant instant diagnosis].

Histotopographic examinations of goiters and scrapes taken as a whole are valuable to the emergency pathomorphological diagnosis of thyroid and endometrial diseases essential particularly for the differentiation of adenomas and well differentiated carcinomas. The examination can be carried out only by treating fresh, non-fixed materials with a deeply cooling knife of the routine cold microtome (Model X). Harris' or Ballard's hematoxylins are best used as elective dyes. The whole instant diagnosis fully described in the paper lasts 8 to 12 minutes.

Diagnosis, Differential↗

[Small thyroid cancer].

Thyroid carcinoma was detected in 1132 of 32500 patients undergoing surgery because of goiter. Small thyroid carcinoma (STC) was found in 245 patients (21.6%) and is divided into the following subgroups: 1) local (focal) microcarcinoma-a focus of a pronounced proliferation, dysplasia and fibrosis up to 1 mm in diameter; 2) invasive dwarf carcinoma of 5 to 15 mm in diameter which is not detected by clinical and instrumental methods; 3) intermediate STC, 1 to 5 mm in diameter. STC had a papillary-follicular structure in 88%, the rest were of a oncocytic and parafollicular structure.

Cell Division↗

[Controversial aspects of verification and classification of thyroid tumors].

20-year experience in the intraoperative study of more than 3000 goiters led the authors to the conclusion that the most correct verification of the pathologic process may be performed only by means of intraoperative stereomorphological and histotopographic examination of the biopsy. In case of nodular hyperplasia of follicular and macropapillary structures the most adequate term is adenomatous goiter. The term borderline thyroid tumor is also suggested although it needs further discussion by both clinicians and morphologists.

Biopsy↗