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Biomedical subjects

B Davidson

Publications and source records attributed to B Davidson.

At least 91 records · Page 5Linked to original sources

Endothelial cell loss following phacoemulsification in the pupillary plane.

Endothelial cell loss following posterior chamber phacoemulsification with and without posterior chamber lens implantation was studied. Postoperative cell counts were taken four months after surgery. Three surgeons participated in this study. Posterior chamber phacoemulsification alone (30 patients) resulted in a mean cell loss of 9%, with a maximum cell loss of 22% in one patient. Posterior chamber phacoemulsification with posterior chamber lens implantation (30 patients) resulted in a mean cell loss of 8% with a maximum cell loss of 26% in one patient. Statistical analysis shows no difference in postoperative cell loss between these two groups.

Aged

Secondary posterior chamber intraocular lens implants.

Secondary posterior chamber lens implants were performed on sixty-nine patients. Although technically the insertions were slightly more difficult than in a primary case, the results were excellent. Only one eye had vision significantly lower than preoperative level, and this, only a drop from 20/25 to 20/40. Three eyes required a second procedure to suture the lens. One eye suffered detachment later with count fingers vision as the final result.

Aged

The Terry surgical keratometer: a 12-month follow-up report.

Postoperative astigmatism was studied in two groups of patients. All patients had undergone phacoemulsification with implantation of a posterior chamber intraocular lens. The incision closure techniques in both groups were identical, with one exception: One group was closed using the Terry keratometer intraoperatively, the second group was closed without the use of this instrument. Two observations are made from the twelve-month data. First, astigmatic error in the Terry group remained constant from the postoperative keratometer readings at six weeks to the twelve-month keratometer readings. Second, while there was a considerable difference in astigmatism at six weeks between the Terry group and the control group (less astigmatism in the Terry group), the differences were no longer apparent at twelve months. Sutures were removed as necessary to improve astigmatism in the control group. No sutures were cut in the Terry group during this twelve-month period.

Astigmatism

The Shearing intraocular lens: a report of 1,000 cases.

Implantation of Shearing and Shearing-style J-loop posterior chamber lenses in 1000 cases was associated with an absence of corneal decompensation and a low incidence of glaucoma, cystoid macular edema, iritis, vitritis and retinal detachment. The low complication rate was attributed to the posterior chamber position of the J-loop lens, which may reduce the movement of intraocular fluid and tissue.

Adult

Inhibition of mitochondrial fatty acid elongation by antibodies to 3-ketoacyl-CoA thiolase.

Antibodies to pig heart 3-ketoacyl-CoA thiolase inhibited almost completely and in a parallel fashion thiolase and the acetyl-CoA-dependent fatty acid elongation system present in an acetone powder extract of pig heart mitochondria. This finding leads to the conclusion that mitochondrial fatty acid elongation occurs by reversal of fatty acid oxidation. Several lines of evidence point to the thiolase-catalyzed condensation reaction as the rate-limiting step in the formation of elongated products. However, the accumulation of hydroxy acids suggests the enoyl-CoA reductase activity is limiting in the synthesis of saturated fatty acids.

Acetyl-CoA C-Acyltransferase

Clinical evaluation of the Terry surgical keratometer.

A study was designed to evaluate the usefulness of the Terry quantitative surgical keratometer as a tool to minimize surgically induced astigmatism. Two hundred and twenty-five phacoemulsifications with Shearing-style implants were performed, using identical technique. Seventy-five control cases were closed without the keratometer and 150 were closed with the keratometer. In the control group, 29.3% cases had corneal astigmatism of 3D or more, compared to 4.6% cases in the keratometer group (P < .01). The total change in astigmatism was 2.64D in the control group and 0.91D in the keratometer group (P < .02). We believe that these data demonstrate the usefulness of the Terry keratometer.

Astigmatism