Oncogenic properties of human viruses.
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Adenoviridae↗
Biomedical subjects
B Decker
Publications and source records attributed to B Decker.
Implementation of the mastery learning/modular curriculum in nurse-midwifery education.
A survey of all nurse-midwifery programs in operation during 1987 was designed to answer the questions: (1) to what extent were elements of mastery learning being implemented in nurse-midwifery programs, and (2) were there patterns of implementation associated with particular organizational characteristics of the programs. Mastery learning was introduced in nurse-midwifery education in 1972; in this study elements of mastery learning were found to be widely implemented in both mastery and non-mastery learning programs. Data about organizational characteristics of the programs revealed them to be homogeneous in several respects. There were no important differences in implementation of elements of mastery learning associated with the organizational characteristics studied.
Curriculum↗
What would Nightingale say?
The letter to Florence Nightingale was written by Bernita Decker as part of a nursing course assignment for our Nurse Educator advisor, Betty Pugh. Florence Nightingale's response to the student was written by Joanne Farley, a Nightingale historian, who recently returned from a trip to England and Ireland to study original Nightingale documents and historic sites.
Education, Nursing↗
Filtration characteristics of the single isolated perfused glomerulus of Myxine glutinosa.
Using an in vitro microperfusion technique, the filtration characteristics of single isolated glomeruli of the Atlantic hagfish (Myxine glutinosa) were investigated. The suitability of the method as a model to study glomerular function was evaluated. Experiments with a protein-free perfusate led to a filtration coefficient Kf (0.189 +/- 0.181 nl x s-1 x mm Hg-1) that was in the same order of magnitude as determined in vitro for other vertebrates. Morphometric analysis on serial thin sections (1 microns) revealed a glomerular capillary surface (A) of 1.84 +/- 0.72 mm2. A linear relationship between glomerular diameter and A allowed the calculation of the hydraulic conductivity Lp (0.618 +/- 0.384 microliter x s-1 x mmHg-1 x cm-2). The data indicate that the isolated perfused glomerulus of M. glutinosa has filtration characteristics similar to higher vertebrates. The glomeruli of M. glutinosa, which in contrast to glomeruli of other animals are easy to dissect, are a suitable model for the study of glomerular filtration and permeability characteristics of vertebrates. An example of a possible application of the model is a study into the effects of adrenaline on glomerular filtration characteristics. Adrenaline led to increases in ultrafiltration pressure (PUF), single nephron glomerular filtration rate (SNGFR) and filtration fraction (FF); Kf remained unaffected.
Animals↗
Collagen fibril organization in the patellar tendon autograft after posterior cruciate ligament reconstruction. A quantitative evaluation in a sheep model.
We replaced the posterior cruciate ligament in 30 skeletally mature sheep with a patellar tendon autograft using the central third of the ipsilateral patellar tendon. The healing autograft was compared with the contralateral posterior cruciate ligament and the patellar tendons and posterior cruciate ligaments of nonoperated animals. The collagen fibril diameters were analyzed using transmission electron photomicrographs of fibril cross sections taken at six periods during the 2 years after surgery. The patellar tendon and posterior cruciate ligament were characterized by a broad, nongaussian distribution of collagen fibril diameters. The autografts shifted to a unimodal distribution by an increase of small-diameter collagen fibrils. The frequency of small-diameter fibrils measuring up to 100 nm was 99% after 2 years. At that time, these small-diameter fibrils represented 91.6% of the area covered by collagen fibrils. The mean diameter of the collagen fibrils in the autografts significantly decreased to 45% of the controls at Week 26 and remained at this level until the end of this study. The percentage of area covered by collagen fibrils per 1 micron 2 was 78% of the controls 2 years post-operatively. This study suggests that the patellar tendon autograft could not reproduce the collagen fibril organization of the posterior cruciate ligament. This may be a biologic factor responsible for inconsistent results in posterior cruciate ligament replacement.
Actin Cytoskeleton↗