Biomedical subjects

B Dmitrović

Publications and source records attributed to B Dmitrović.

21 records · Page 2Linked to original sources

PubMedDate not supplied

[Total allergen-specific IgE antibodies in the serum and skin reactivity induced by a mixture of pollens in allergic individuals].

Skin puncture test is fast and precise method for revealing IgE-mediated allergen hypersensitivity. In the diagnosis of pollinosis and other atrophic diseases, expensive tests for revealing the allergen-specific IgE antibodies in the serum are frequently inaccessible. The subject of our investigation was how and if the skin test with mixture of pollen could replace the expensive in-vitro method in diagnostic procedure. In 41 patients with pollinosis were performed skin tests by the mixture of pollen of grass, weeds and trees (produced by Torlak Institute, Belgrade) and determined the concentration of overall and allergen-specific IgE serum (EIA, enzyme immuno-assay, Pharmacia Uppsala; RAST Phadesim, multidisk, Pharmacia). Obtained results pointed out that the sex of investigated subjects did not influence the size of skin reaction in case when the pollen mixture (grass, weed or trees) was used. With high significance rate was established that in skin puncture test, just the size of the reaction, defined by 5 mm papule or larger, indicated the hypersensitive person. We consider that this can be taken as the diagnostic criterion and replace in-vitro method for determination of allergen-specific IgE antibodies in serum. Also, overall IgE of serum positively correlated (p < 0.05) with the size of skin reaction only in the persons with extremely high concentrations (RAST class 4) allergen-specific IgE antibodies in serum.

Adolescent↗

PubMedDate not supplied

[Civilian massacre near Podravska Slatina, 3 September 1991].

Twenty one civilians, 5 women and 16 men, were found dead in their doorways and yards after Serbian terrorists attacked the village of Cetekovac on 3 September 1991. The age of the decedents ranged from 18 to 91 years. The oldest victims were women (aged 63, 68, 72, 86 and 91). The wounds found on 19 decedents were characteristic of the long-range gunshot wounds, with projectiles fired mostly from the back or/and the side of the body. The autopsy of one decedent (J. B.) revealed that he died from two stabbing wounds and that those were the only wounds inflicted to the body. The body of the decedent (M. S.) was heavily carbonized so that the cause of the death or even whether he was alive when his body was set on fire could not be estimated.

Adolescent↗

PubMedDate not supplied

[Granular cell tumor].

Eighteen granular cell tumors (GTC) were detected from January 1976 until September 1988. GTC is found in 0.03% of all the biopsy specimens. Women have been found to be affected more frequently. The most common anatomic sites where it appears are the skin and subcutaneous tissue of the trunk and the vulva. Tumors ranged in sizes from 0.6 to 4 cm (average 1.5 cm). One patient had multiple lesions. The lesions show typical histologic features, usually with ill-defined edges. The preoperative diagnoses were never determined as GTC. Pseudoepitheliomatous hyperplasia of the overlying epithelium led to the wrong intraoperative diagnosis of squamous cell carcinoma in one lingual GTC. On gross inspection, one breast GTC was mistaken for invasive carcinoma with desmoplasia. One vulvar lesion was previously diagnosed as pseudo-decidual reaction. Malignant behaviour could not have been noticed, since it is of importance to pathologists and clinicians not to misinterpret this lesion as carcinoma.

Adolescent↗