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Biomedical subjects

B Drzewiecka

Publications and source records attributed to B Drzewiecka.

At least 19 recordsLinked to original sources
PubMed2004

Reflex respiratory responses to progressive hyperoxic hypercapnia and normocapnic hypoxia in normocapnic and hypercapnic obstructive sleep apnea patients.

Ventilatory responses to progressive hypercapnia were analyzed in the normocapnic and hypercapnic obstructive sleep apnea patients (OSA). The rebreathing hypercapnic and hypoxic tests were performed using the computerized equipment (Lungtest, MES), according to Read's method. The ventilatory response to hypoxia was impaired in all OSA patients. Concerning the hypercapnic ventilatory response, there were no differences between the OSA patients with normal end-tidal PCO(2) and controls. Nine moderately hypercapnic OSA patients showed a right shift with a normal slope of the regression curve describing the relationship between the end-tidal PCO(2) and minute ventilation. In contrast, three severely hypercapnic OSA patients showed a right shift with a decreased slope of this regression curve. We conclude that awake OSA patients who developed hypercapnic ventilatory insufficiency showed an impaired hypercapnic defense reaction.

Carbon Dioxide↗
PubMed2000

[Campylobacter in surface waters for communal purposes in Bydgoszcz region].

The aim of our work was to determine the frequency of Campylobacter occurrence in surface water taken from lakes and rivers. For this purpose the membrane filters technique in microaerophylic conditions and Columbia Agar with the antibiotics addition as the culture medium were used. The genera of Campylobacter were determined. At the same time the purity of water's samples was estimated. The total number of bacteria as well as the number of Coli spp. were determined. The results indicate that 33% of water samples were contaminated with Campylobacter (predominated C. coli and C. jejuni). The percentage increased with the degree of contamination with Coli.

Campylobacter↗
PubMed1997

Radiation-induced oxidative DNA base damage and its repair in nuclear matrix-associated DNA and in bulk DNA in hepatic chromatin of rat upon whole-body gamma-irradiation.

In the present work, we examined the formation and repair of DNA base damages induced by gamma-irradiation in different fractions of rat hepatic chromatin. Animals were exposed to radiation with the dose of 10 Gy. Nuclear matrix DNA and whole chromatin were isolated from the liver of rats killed before and in different time after irradiation. In those samples the pyrimidine-derived and the purine-derived modified DNA bases were identified and quantitated by gas chromatography/isotope-dilution mass spectrometry with selected-ion monitoring. We found elevated levels of modified DNA bases over control values after whole body irradiation in both matrix DNA and bulk chromatin samples. Our results suggest that modified bases are preferentially removed from matrix DNA then bulk chromatin.

Animals↗
PubMed1989

[Effect of marked obesity on the emotional status of children].

Fifty children with overweight exceeding 50% of the expected weight were studied for establishing the occurrence of emotional disturbances caused by lack of acceptance by peers. Obese children were found to suffer often from discrimination by their schoolmates which was, in some degree, connected with their low fitness. This may lead to various emotional disturbances requiring even psychotherapeutic measures.

Adolescent↗
PubMed1975

Comparison of the septal lesion effects on visual and spatial discriminations in rats.

Postoperative performance in acquisition and reversal learning of septal rats was investigated and compared with control rats in three experiments. Experiment I involved a simultaneous black-white discrimination task. The number of errors in normal and septal rats was similar in acquisition and reversal learning. Both septal and normal rats manifested directional response sets. Experiment II examined a position habit discrimination. Acquisition was similar in septal and normal rats, while reversal learning was impaired in septal rats. Experiment III, which investigated a position habit discrimination with available irrelevant visual stimuli indicated that both acquisition and reversal learning were impaired in operated animals. Results suggested that septal rats utilize response produced cues to control their behavior, but the enhanced orienting response to the visual stimuli interferes with the proprioceptive stimuli.

Animals↗