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Biomedical subjects

B Dumoulin

Publications and source records attributed to B Dumoulin.

7 recordsLinked to original sources
PubMed1984

[Influence of lithium on magnesium levels in the plasma, erythrocytes and brain of rats].

Intra peritoneal administration of LiCl to rat with a single dose or every day during a week shows that the correlation of brain Li with erythrocytes Li is better than the same correlation with plasmatic Li. With a single dose of Li the variation of the Li level doesn't give significant variations of Mg. With repetitive administrations of Li (near that which occurs in actual therapeutic treatment) we show (44 pairs of results with p less than 0.001) that the increase of Li in erythrocytes is correlated with a decrease of Mg in erythrocytes and an increase of this ion in plasma. The authors demonstrate that the nervous cells don't release Mg when Li get in the brain.

Animals↗
PubMedDate not supplied

Reference values of total respiratory resistance and reactance between 4 and 26 Hz in children and adolescents aged 4-20 years.

In 403 healthy subjects, 4 to 20 years of age, we measured total respiratory resistance (Rrs) and reactance (Xrs) between 4 and 26 Hz. When possible, vital capacity and forced expiratory volume in one second were also determined. The Rrs and Xrs vs frequency data depend on age or height, on sex, and slightly on weight. During growth, Rrs and the frequency dependence of Rrs decrease while Xrs increases. Only part of these changes may be explained entirely by a size effect. The variations with growth of ventilation unevenness, of airway wall compliance and of the topographic distribution of airway resistances probably also play a role. The influence of the interactions between height and age, and height and weight on Rrs and Xrs differ between sexes. Adult values for Rrs and Xrs are attained at the age of 15 years in girls and 18 years in boys.

Adolescent↗
PubMedDate not supplied

[Changes in cerebral calcium, sodium and potassium after single or repeated administration of lithium in the rat].

A single administration (IP) of lithium chloride in the rat induces a decrease in erythrocyte calcium, proportional to the lithium level (p less than 0.01) and a diminution in cerebral calcium (p less than 0.001) which is accompanied by decrease in cerebral sodium and potassium levels (p less than 0.001). Repeated administration (IP + VO) has the same cerebral effects. The authors report that the reversible decrease in calcium, sodium and potassium, resulting from an increase in cerebral lithium levels, can be demonstrated on sampling at 1.30 and 3 hours (IP), or at 12 hours (VO). These results are relevant to the treatment of manic illnesses using calcium antagonists.

Administration, Oral↗