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Biomedical subjects

B E Dietrich

Publications and source records attributed to B E Dietrich.

7 recordsLinked to original sources
PubMed1986

Congenital hemangiopericytomas of skin.

A case of multiple congenital hemangiopericytomas of skin treated by surgical excision is presented. No recurrence of the lesions has occurred after a period of 2 years.

Antigens↗
PubMed1980

Eosinophilic gastroenteritis.

Eosinophilic gastroenteritis consists histologically of a purely eosinophilic infiltration of small bowel and stomach walls. This is manifested radiologically in the small bowel as a thickening of the circular folds and wall without mucosal ulceration or any other local abnormality, either over much of its length or in a shorter segment. Many of the other causes of pure fold and wall thickening can be excluded by correlation with the clinical presentation so that this condition, although rare, should in the right clinical setting be considered by the radiologist. The typical clinical features consist of cramps, diarrhoea, distension, nausea and vomiting, either as a single subacute episode or with an intermittent history going back months or years, and frequently in a patient with a personal or family history of asthma or other allergic disorders. The eosinophilic infiltration may spare the mucosa in which case per-oral biopsy methods would give negative results. The only means of proving the diagnosis would then be by laparotomy to obtain a full thickness biopsy. However the radiological and clinical features, combined with a therapeutic trial of corticosteroids which rapidly reduce the clinical, radiological and haematological abnormalities, may be sufficient to avert this. The two cases described illustrate many of these features but in addition, unlike most other published cases, they showed neither radiologically visible gastric involvement nor peripheral blood eosinophilia.

Aged↗
PubMed1979

Fatal veno-occlusive disease of the liver after chemotherapy, whole-body irradiation and bone marrow transplantation for refractory acute leukaemia.

Rapid onset of liver failure with fatal outcome occurred in a young woman after successful bone marrow transplantation undertaken for refractory acute leukaemia. Centrilobular necrosis was demonstrated at autopsy and was attributed to prior cytotoxic chemotherapy, possibly potentiated by the total-body irradiation that was used in preparation for the transplant. This association between liver damage and prolonged drug therapy, coupled with the short median survival currently achieved within these chemotherapy regimens, has initiated an evaluation of bone marrow transplantation in patients with leukaemia during the first complete remission, rather than at a later stage when cumulative drug toxicity to the liver may have taken place.

Adolescent↗
PubMed1975

Sclerosing haemangioma of the lung. A case report.

A case of pulmonary sclerosing haemangioma composed of blood-filled cavernous spaces separated by septa containing sheets of uniform, epithelioid-type cells and numerous mast cells is described. Although the histogenesis has not been conclusively established, the appearances in this case favour a primary vascular lesion. The variable histological patterns observed in this tumour may cause problems in diagnosis; the differentiation from haemangioma, haemangiopericytoma, pulmonary chemodectoma and benign clear cell tumour of the lung is discussed.

Aged↗