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Biomedical subjects

B E Golinko

Publications and source records attributed to B E Golinko.

6 recordsLinked to original sources

Side effects of dextroamphetamine and methylphenidate in hyperactive children--a brief review.

Four of the most commonly reported side effects of dextroamphetamine ( Dexedrine ) and methylphenidate (Ritalin), viz., anorexia, insomnia, stomach pains, and weight loss, were reviewed, with special attention to growth suppression accompanying weight loss. The available evidence indicates that the effects of insomnia, anorexia, and stomach pains are transient and diminish as treatment continues and as medication is properly managed. There is evidence for growth suppression accomapnying weight loss, and possibly some suppression of stature, but these effects are not long-lasting and, from existing evidence, seem to have little effect on adult height or weight.

Anorexia↗

Side effects of dexedrine in hyperactive children: operationalization and quantification in a short-term trial.

1. Four common side effects of dexedrine use (viz., anorexia, insomnia, stomach pains, and weight loss) were operationalized and quantified for use by parents in monitoring these effects over a 6 week clinical trial. 2. A weighted summary score, reflecting the frequency and intensity of each side effect, was used to determine the magnitude of each effect during treatment. 3. Four hyperactive children taking 2,5 mg twice daily, and six other hyperactive children taking either 5 or 10 mg twice daily, served as subjects. 4. Results indicated that the average weighted summary scores for all effects did not exceed minimal levels as defined in this study, regardless of dosage. 5. The implications, importance, and usefulness of this side effects scale in treating hyperactive children were discussed.

Anorexia↗