PubMed Health⌕ Search

Biomedical subjects

B E Robinson

Publications and source records attributed to B E Robinson.

90 records · Page 5Linked to original sources
PubMed1982

Suppression of responses to cryptococcal antigen in murine cryptococcosis.

Subpopulations of spleen cells responsible for responsiveness and unresponsiveness to cryptococcal antigen in vitro were identified. Lymphocytes which responded in lymphocyte transformation (LT) assays were nylon wool nonadherent and theta antigen positive. These lymphocytes required the presence of an accessory cell which could be supplied by normal peritoneal exudate cells. Spleen cells taken from mice which had been infected for 3 to 15 days were tested to determine their ability to respond to cryptococcal antigen in LT assays. A minimal response was detected at the ninth day of infection. The response of infected spleen cells was attributed to a nonadherent lymphocyte. Nonadherent spleen cells of infected animals had enhanced responses after removal of adherent cells and addition of normal peritoneal exudate cells. Suppressor cells were detected in the spleens of infected mice by the 12th day of infection and thereafter. A nonadherent suppressor cell was identified, but indirect evidence suggested that an adherent cell could also be present in infected spleens.

Animals↗
PubMed1982

Sex role endorsement among homosexual men across the life span.

This study assessed the sex role endorsement of homosexual men at different ages across the life span. A sample of homosexual men from dignity chapters in the northeastern, midwestern, southern, southwestern, and western United States was mailed a demographic questionnaire and th Bem Sex Role Inventory. Respondents were classified into four age brackets and categorized as androgynous, masculine, feminine, and undifferentiated. A pattern of diverse sex role endorsement was found from adolescence to maturity in which gay men were equally androgynous, masculine, feminine, and undifferentiated at each age level. This finding contradicted an earlier study of heterosexual men that reported increasing numbers of androgynous males with age. The contrast suggests that the sex role endorsement of gay men may be very different from their heterosexual counterparts. It was further suggested tht gay men are capable of meshing masculine and feminine aspects of their personalities early as well as later in life, that gay men do not comprise a homogeneous group, and that the stereotype of cross-gender role endorsement is unfounded.

Age Factors↗
PubMed1982

Issues and problems related to the research on teenage fathers: a critical analysis.

Although there are few research studies on adolescent fatherhood, recently sufficient investigations have occurred to merit a critical analysis. In general, research in this area is marred by certain methodological deficiencies. Research in adolescent pregnancy generally ignores the fathers involved, and data on teenage fathers are often inferred or confounded by the use of biased report techniques. Retrospective and post hoc analyses often render inaccurate conclusions, and sampling methods generate unrepresentative subject pools. This article will demonstrate the ways these issues contaminate knowledge about teenage fathers.

Adolescent↗
PubMed1982

Sex-role orientation of gay fathers versus gay nonfathers.

This study compared the sex-role orientation of 30 gay fathers and 30 gay nonfathers from the Northeastern, Midwestern, Southern, Southwestern, and Western United States. Scores from the Bem Sex-role Inventory were analyzed by a chi squared test of independence. Analysis indicated that gay men who father children are no more masculine than gay men who do not father children. The myth linking masculinity and gay fatherhood was refuted, and these findings were presented as further evidence that sexual behavior and sex-role orientation are unrelated phenomena and develop out of separate experiences.

Adolescent↗
PubMed1979

Fatal mycotic pulmonary disease of captive American alligators.

Fatal pulmonary disease occurred in two captive American alligators. The entomopathogenic fungus, Beauveria bassiana, was isolated from pulmonary lesions in both alligators. An extended hibernation period because of a severe winter and a failure of the zoo heating system may have predisposed the alligators to infection.

Alligators and Crocodiles↗
PubMedDate not supplied

Are hyperplastic rectosigmoid polyps associated with an increased risk of proximal colonic neoplasms?

Diminutive polyps are frequent findings on screening flexible sigmoidoscopy. To determine the significance of distal diminutive polyps, we conducted a prospective study of 162 asymptomatic, average-risk subjects who were 50 years of age or older. Subjects were divided into four groups: 42 control subjects with no polyps in the rectosigmoid, 66 subjects with at least one diminutive adenoma in the rectosigmoid, 12 subjects with a mixed hyperplastic-adenomatous polyp in the rectosigmoid, and 42 subjects with only hyperplastic polyps in the rectosigmoid. Total colonoscopy was performed on all subjects. The prevalence of proximal adenomas was 42% in the adenoma group, 25% in the mixed group, 14% in the hyperplastic group and 12% in the control group. The prevalence of proximal adenomas was significantly higher (p = 0.006) in the adenoma group as compared with the control and hyperplastic groups. Increasing age was associated with an increased prevalence of proximal adenomas. Nearly two thirds of those over 65 years of age with distal diminutive adenomas had proximal colonic neoplasms. These results indicate that diminutive rectosigmoid adenomas are good markers for proximal neoplasms. Rectosigmoid hyperplastic polyps are not associated with an increased prevalence of proximal neoplasms. Total colonoscopy is not indicated if hyperplastic polyps are the only finding on flexible sigmoidoscopy.

Aged↗
PubMedDate not supplied

Therapeutic uses of sexually explicit materials in the United States and the Czech and Slovak Republics: a qualitative study.

This study investigates the reflections of 279 U.S. and Czech and Slovak mental health and health professionals about their use of sexually explicit materials. Professionals were 2.6 times as likely to cite specific instances when their use of sexually explicit materials was useful with their clients and students than they were to cite instances when such materials were not useful. In addition, no significant differences were observed between the ways in which U.S. and Czech and Slovak mental health and health professionals evaluated these materials. The article presents several suggestions for the judicious and efficacious use of sexually explicit materials in therapy or in the classroom in either Western or Central European settings.

Adult↗
PubMedDate not supplied

Review of Medicare's proposed hospice eligibility criteria for select noncancer patients.

Recent events have challenged our health system to increase access to and provide high quality care for patients near the end of life. Simultaneously, Medicare is developing review policies to determine eligibility for hospice patients with select noncancer diagnoses. The purpose of this study was to determine whether the proposed policies met one of their chief goals: accurate identification of patients with a less-than-six-months prognosis. Only 35 percent of 104 patients who died within six months of admission to the hospice used for this study, LifePath Hospice, met the Medicare proposed criteria for hospice eligibility. The median and mean survival time of the sample was 14 and 30 days respectively. Based on this review, it is recommended that Medicare alter their proposed review policies and not limit access to hospice eligible patients who desire and are in need of such services.

Chronic Disease↗
PubMedDate not supplied

Hospice.

Explore the source record for details and available documents.

Florida↗
PubMedDate not supplied

Hematopoietic growth factors.

Hematopoiesis is a complex process that underlines the production of multiple highly specialized cells. The intricate mechanisms involved in this process include both positive and negative feedback by humoral activities, pluripotent stem cell selfrenewal and differentiation, and local interactions between stromal components of the hematopoietic microenvironment and various stem and progenitor cells. A group of hematopoietic growth factors, as well as their genes and chromosomal locations, have been identified. Advances in biochemistry and molecular biology led to the purification, genetic sequencing and molecular cloning of these glycoproteins. They include interleukin-3 (IL-3), granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), macrophage colony-stimulating factor (M-CSF) and erythropoietin (EPO). The biologic specificity of these substances is defined by their ability to support proliferation and differentiation of hematopoietic cells in a semisolid clonal assay system. These factors share certain characteristics, including their ability to stimulate the function of mature cells, their overlapping activity affecting progenitor cells of several lineages, and their direct and indirect actions on nonhematopoietic cells. Trials using hematopoietic growth factors demonstrated their remarkable efficacy in a variety of clinical settings.

Animals↗
PubMedDate not supplied

Obesity: a move from traditional to more patient-oriented management.

BACKGROUND: Family physicians have been encouraged to be aggressive in their treatment of obesity in their overweight patients. This article examines our traditional management of obesity and presents a management approach that is relatively safe, healthy, and patient-oriented. METHODS: A review of the literature on obesity and its treatment was performed by searching MEDLINE, PsychINFO, ERIC, and SOCA data bases from 1980 to 1993. Additional references were accessed by cross-referencing the bibliographies of the articles obtained through this search. RESULTS AND CONCLUSIONS: Both physicians and society in general tend to be biased against obese individuals, and this bias has negative consequences in that it reinforces patients' negative stereotypes about their fatness and could contribute to their avoidance of physicians. To circumvent this tendency, physicians should make a conscious effort to treat their obese patients with understanding and respect and to offer treatment that optimizes their risk-benefit profile. Regardless of weight, all patients should be asked about their diet and exercise history, and a brief mental status evaluation should be performed to screen for eating disorders and other psychosocial disorders. In addition, all patients should be encouraged to follow a healthy lifestyle, which includes regular, moderate exercise and a balanced, low-fat diet. Repeated dieting should be avoided, because it can produce more harm than benefit by contributing to binge eating, loss of self-esteem, and increased risk of sudden death and cardiovascular disease. Thus, only obese patients who have never attempted comprehensive weight reduction programs should be encouraged to try such a program. Patients who have severe obesity that interferes with their lives or who have moderate obesity and a comorbid condition can be offered a gastroplasty or gastric bypass procedure, coupled with an explanation and discussion of the success and failure rates involved. Regardless of whether patients are able to lose weight, the family physician can still provide long-term support and care and encourage a healthy lifestyle in these patients.

Combined Modality Therapy↗