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Biomedical subjects

B E Schwarz

Publications and source records attributed to B E Schwarz.

At least 19 recordsLinked to original sources
PubMed1994

Presumed paranormal linkage of rings.

Examples are presented in the SORRAT experiments of: (1) presumed paranormally linked human aortic rings and their teleportation into a sealed, glass globe; (2) videographed experiments with Joe Nuzum, paragnost, while in a trancelike state, accomplishing linkage of a class ring on his finger to one key of several held in a researcher's hand; and (3) in a different experiment linking two rubber bands of several which were held in a researcher's hand. X-ray and MRI studies tend to confirm the genuineness of these mind-over-matter psychosomatic effects. Further linkage experiments are described including videographed linking and delinking of rubber bands, and a videographed linking and delinking of a gold seamless ring and brass nut. It is speculated that these experiments illustrate some degree of conscious, volititional control and might have analogous and overlooked aspects and possibilities in human biology and nature, and that these are overripe areas for intensive parapsychiatric investigation.

Adolescent↗
PubMed1993

A preliminary report of Norplant implant insertions in a large urban family planning program.

During the 21-month period between August 1, 1991, and April 30, 1993, 2,358 women received Norplant system insertions in either Parkland Memorial Hospital or the Dallas Maternal Health and Family Planning clinics. Forty-three percent of these women were teenagers with 14% 16 years of age or less. Overall, 431 patients received Norplant implants insertions postpartum prior to discharge from the hospital. To date, 138 Norplant systems have been removed, with the proportion of contraceptive implant removals among teenagers being essentially the same as that in more mature women. Of the reasons given by women discontinuing the Norplant system, an unanticipated high incidence of pain in the arm containing the implants, hair loss, and mood changes were noted. We have found the Norplant system to be a highly effective and highly acceptable contraceptive method for a large number of indigent women.

Adolescent↗
PubMed1991

Effect of age on gastric acid secretion and serum gastrin concentrations in healthy men and women.

The effects of age on basal, meal-stimulated, and human gastrin-17-stimulated gastric acid secretion rates and serum pepsinogen concentrations were evaluated in 41 healthy men and women. Older subjects (ages 44-71 years; mean, 57 years) had higher mean basal, meal-stimulated, and gastrin-17-stimulated acid secretory rates and basal serum pepsinogen I and II concentrations than younger subjects (ages 23-42 years; mean, 33 years). Age-related differences in acid secretion were especially prominent in men, and age-related differences in serum pepsinogen I and II concentrations were more prominent in women. Higher gastric acid secretion rates in older subjects could not be explained by body size (height, weight, body surface area, or fat-free body mass) or by the higher incidence of infection with Helicobacter pylori. Using a multivariate linear regression model, age had an independent positive effect on acid secretion, and H. pylori infection had an independent negative effect. It was concluded that aging is associated with an increase in gastric acid secretion in humans, especially in men, while infection with H. pylori is associated with lower acid secretion rates.

Adult↗
PubMed1981

Premature labor.

Explore the source record for details and available documents.

Arachidonic Acid↗
PubMed1980

Initiation of human parturition. XI. Lysosomal enzyme release in vitro from amnions obtained from laboring and nonlaboring women.

In the present investigation, we sought to ascertain whether an alteration in the physiology of amnionic lysosomes could be demonstrated in association with normal human labor at term. We reasoned that perturbation of the lysosomes of amnion would be associated with a greater rate of release of known lysosomal marker enzyme activity from this tissue. In order to investigate this possibility, we employed discs of amnion tissue which were incubated in medium containing sucrose (0.25M). We observed that the rate of release of lysosomal marker enzyme activity, N-acetyl glucosaminidase, into the incubation medium from amnion tissue obtained from laboring women was greater than the rate of release of the same enzyme activity from amnion tissue obtained from women who were not in labor. During incubation, there was no detectable release of lactate dehydrogenase, a cytosolic marker enzyme, which attests to the viability of the amnion tissue during the experiment. These findings are consistent with the view that there is an alteration in the physiology of lysosomes of the amnion associated with human labor at term, a finding which is supportive of a role for lysosomes of the human fetal membranes in the initiation of human parturition.

Acetylglucosaminidase↗
PubMed1980

Sonographic findings and clinical correlations in molar pregnancy.

From a group of 313 women referred for pelvic sonography because of clinical suspicion of molar gestation and 5 additional sonographically diagnosed but clinically nonsuspect cases of hydatidiform mole, 50 were ultimately proved to have a hydatidiform mole. There were 2 false-positive and 2 false-negative sonographic interpretations. In the 50 patients having a proved molar gestation, predelivery uterine volume was sonographically calculated, and the presence and size of theca lutein cysts was recorded. Correlation of gestational age estimated from sonographically measured intrauterine volume to clinical estimation of uterine size revealed a tendency to overestimate gestational size by a mean of 3.5 weeks. Theca lutein cysts were detected in 10% of patients by clinical examination, whereas they were detected by sonography in 37% of cases. Seven of 50 molar pregnancies were associated with post-molar trophoblastic disease. Patients with a volumetrically large-for-dates uterus or with theca lutein cysts did not have a higher incidence of postevacuation invasive mole or choriocarcinoma. Sonography remains an excellent diagnostic technique, but cannot predict the postevacuation clinical course.

Adolescent↗
PubMed1979

5 alpha-Reductase activity in human placenta.

The concentration of 5 alpha-pregnane-3,20-dione in peripheral blood of pregnant women is higher than that found in blood obtained from nonpregnant women throughout the luteal phase of the ovulatory cycle. The in vitro synthesis of 5 alpha-reduced pregnanes from [3H]progesterone by placental tissue was investigated using tissue minces and homogenates in the presence of added nicotinamide-adenine dinucleotide phosphate. The metabolites, [3H]5 alpha-pregnane-3,20-dione and [3H]3 beta-hydroxy-5 alpha-pregnan-20-one, were isolated and characterized employing a combination of chromatographic techniques, derivative formation, and crystallization with authentic [14C]5 alpha-pregnane-3,20-dione and [14C]3 beta-hydroxy-5 alpha-pregnan-20-one to constant 3H:14C ratios. In short-term incubations with placenta homogenates, the apparent pH optimum for the synthesis of 5 alpha-pregnane-3,20-dione was 8.8. There was no evidence for the formation of 5 beta-reduced pregnanes from [3H]progesterone by placental tissue. The in vitro metabolism of [3H]progesterone by minces of five term placentas, during 1 hour incubations at pH 7.4, was studied. The rate of formation of 5 alpha-pregnane-3,20-dione varied from 109 to 197 pmoles/gm placental tissue/hr.

3-Oxo-5-alpha-Steroid 4-Dehydrogenase↗
PubMed1978

Initiation of human parturition. IX. Progesterone metabolism by placentas of early and late human gestation.

In in vitro studies it was found that, in the presence of added NADPH, the human placenta metabolizes progesterone to 20alpha-hydroxy-4-pregnen-3-one at increasing rates as pregnancy advances. A fivefold increase in 20alpha-hydroxysteroid oxidoreductase activity is observed in term placentas compared with the enzymic activity of placentas of 12 to 20 weeks' gestation (368 +/- 53 pmoles/mg protein/hr vs 71 +/- 8 pmoles/mg protein/hr). The 5alpha-reductase and 3beta-hydroxysteroid oxidoreductase activities were similar in placentas obtained from early and late human pregnancies.

20-Hydroxysteroid Dehydrogenases↗