PubMed HealthSearch

Biomedical subjects

B Edel

Publications and source records attributed to B Edel.

4 recordsLinked to original sources

[Danger of infection from communion cups--an underestimated risk?].

The problem of a risk of infection from the common use of chalices has been discussed controversially in literature. Opinions were mainly based on laboratory experiments and theoretical considerations. The authors examined bacterial counts and species existing under normal conditions after communion. For this purpose, contact samples were taken from the inside and outside of chalices at the rim. Staphylococci and alpha-haemolytic streptococci were found on all chalices examined. On more than 80%, there were apathogenic micrococci, nonhaemolytic streptococci, apathogenic neisseria and apathogenic corynebacteria as well as lactobacilli and bacilli. Staphylococcus aureus was found on 26.4% of chalices. Although the risk of infection for healthy persons from a commonly used chalice can be rated as low, it should not be underestimated for persons with reduced resistance and immunocompetence, or with reduced defences as a result of therapeutic measures. From the hygienic point of view, the most favourable approaches to avoid infection would be the use of individual chalices for all participants in the communion or the immersion of wafers or bread in wine or in grape juice by the priest (intinction).

Bacteria

The value of a postoperative radiation therapy in FIGO stage I and II endometrial cancers.

PURPOSE: The incidence of endometrial cancer has increased considerably within the last decades. Due to early symptoms more than 88% of all patients present initially with FIGO stage I or II disease. PATIENTS AND METHODS: One hundred and forty-four patients out of 192 patients with stage I endometrial cancers received surgical treatment alone. Like the remaining 48 patients 39 out of 65 patients with stage II tumors received adjuvant radiation therapy with 50 Gy to the true pelvis. RESULTS: Independent on the chosen treatment results in stage I were influenced by the depth of myometrial invasion (p = 0.023). With a crude 5-year survival rate of 88% patients with less than 33% reached life expectation of matched healthy women. With deeper infiltration crude survival rates were as low as 77%. In stage II tumors 5-year crude survival was elevated 60 to 80% independent on the depth of myometrial infiltration by adjuvant radiation therapy (p = 0.11). CONCLUSIONS: Despite its potential curability and the general knowledge that the prognosis of endometrial carcinomas is governed by a number of factors there are no generally accepted standard treatment modalities available Thus there is great demand for randomized clinical trials.

Adult

[Effect of phosphate and inhibitors of protein synthesis on the growth and tentoxin production of Alternaria alternata (Fr.) Keissler].

The synthesis of a phytotoxic substance, tentoxin, by Alternaria alternata (Fr.) Keissler is negatively controlled by inorganic phosphate. We show here that the influence of phosphate on the production of this secondary metabolite is time-dependent. By using inhibitors of protein synthesis (p-fluorphenylalanine, cycloheximide) together with a resuspension technique, attempts were made to find out when the enzymes responsible for tentoxin synthesis are formed.

Alternaria

Nonisothermal kinetics with programmed temperature steps.

Data required for predicting the stability of an active principle in solution can be obtained by two kinetic methods. With the isothermal method, the degradation rate constants are determined at different temperatures, which are kept constant throughout the experiment. With the nonisothermal method, the temperature is increased with time. This paper describes a nonisothermal kinetic method in which the temperature is increased in consecutive equal steps. The results are compared with those obtained by the conventional isothermal method. The values for the activation energy are approximately the same by both methods. Although the technique of nonisothermal kinetics demands sophisticated equipment and high experimental accuracy, it provides a continuous picture over a wide temperature range.

Chemical Phenomena