Fibre density in demyelinating and axonal polyneuropathies.
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Biomedical subjects
Publications and source records attributed to B Emeryk.
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The authors describe two cases of extramedullary tumours in the vertebral canal with long (7 and 15 years) course without pains and with clinical manifestations simulating Charcot-Marie-Tooth disease. It is stressed in conclusion that sporadic cases of this disease with involvement of the lower extremities only, with normal conduction velocity in the peroneal nerves should be differentiated against spinal cord tumours situated in the vertebral canal.
The results of jitter measurements in 15 patients with myasthenia gravis and 10 control group persons are presented using single fiber emg (SFEMG) method during weak voluntary activation and intramuscular AS. The method of AS is described, advantages of its use in evaluation of neuromuscular transmission disorders, some limitations and technical traps that the investigator encounters are presented. Jitter values obtained by both methods are compared and existing differences are discussed taking into account two variants of jitter origin.
In a group of 31 women with myasthenia the urinary excretion of 17-ketosteroids and their fractions (11-deoxy-17-ketosteroids, dehydroisoandrosterone) and 17-hydroxycorticosterone were determined. A statistically significant decrease was observed in the excretion of these substances. Besides that, the plasma cortisol level was determined in these patients and the results obtained in the whole group were at the lower normal range of the laboratory and in 40% of cases they were significantly lower (p less than 0.01). The obtained results may suggest that adrenocortical hypofunction exists in many cases of myasthenia. The pertinent literature is reviewed.