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Biomedical subjects

B Entwistle

Publications and source records attributed to B Entwistle.

9 recordsLinked to original sources

The immunogenicity of Haemophilus influenzae: meningococcal protein conjugate vaccine in Polynesian and non-Polynesian New Zealand infants.

OBJECTIVE: To examine the comparative immunogenicity of the Haemophilus influenzae type b-meningococcal protein (PRP-OMP) conjugate vaccine in Polynesian and non-Polynesian New Zealand infants. METHODOLOGY: Fifty-six Polynesian and 53 non-Polynesian infants aged 2-7 months recruited from primary health care settings in Auckland received a two-dose primary series of PRP-OMP. A sub-sample of 83 participants received a booster dose of PRP-OMP at 12-16 months of age. Anti-PRP antibody concentrations were measured in pre- and post-vaccination blood samples. RESULTS: Antibody responses consistent with long-term protection (> or = 1.00 microgram/mL) were observed in 72, 85 and 95% of children following the first, second and booster doses. CONCLUSIONS: Despite differences in disease epidemiology, PRP-OMP was highly immunogenic in Polynesian and non-Polynesian infants.

Antibody Formation↗

Dental caries in permanent teeth in children of migrant farm workers.

A 1984 study of dental disease in 534 children (aged 6-15) of migrant farm workers in Colorado found that the prevalence of disease for this population continues to exceed the national and regional average. The mean DMFS was 3.56 with only 23 per cent caries free compared to a regional non-migrant DMFS mean of 2.50 with 44.7 per cent caries free. Results indicate that the children of migrant farm workers should remain a priority in preventive and restorative dental care programs.

Adolescent↗

Current and future projections of dental school patient availability.

Results of a mail questionnaire received from 59 United States and ten Canadian dental schools indicated a potentially serious problem in obtaining and maintaining dental teaching patients. Most schools report at least one shortage that could eventually compromise the clinical education process. Future projections indicated a continuing problem due to perceived reductions in disease incidence. The importance of addressing this problem is accentuated by the dental schools' educational mission to provide sufficient clinical experiences in all subject areas of dentistry. The information derived from the questionnaire should provide background for dental administrators as they respond to the patient availability problem.

Canada↗

Changing patient needs and their impact on clinical education.

Dental records of 1,800 clinic patients were examined in nine U.S. dental schools. The objective of the study was to identify what changes, if any, occurred over the five-year period between 1978 and 1982 in dental clinic patient treatment needs. Patients were found to be older at the time of entry into the clinical system and they required less operative treatment, fewer opposing full dentures, and less fixed bridgework. Increases in single full dentures and partial dentures were recorded. No changes were observed in endodontics, periodontics, or oral surgery treatment needs. These findings present a potentially serious problem in affected areas that may lead to a decline in the availability of sufficient experiences for the clinical training of dentists.

Adolescent↗

Sharing best practice: developing a Web-based database.

This article reports on the development of a web-based interactive database that was designed to facilitate the dissemination of practice development, research and audit projects across a large NHS trust. A multidisciplinary team worked collaboratively to design the database in order to ensure that it incorporated features which made it easy for the end user. Concise structured information on each project was recorded and search facilities incorporated to facilitate access to information. Hyperlinks to other web pages on the Internet and the Trust intranet were created and full reports/publications of projects were included for those who wanted more information. The subsequent implementation across the organization involved promoting the database, helping practitioners develop skills to access information, setting up quality review procedures for projects and evaluating its use. The development of the database has highlighted that time, the availability of computers in clinical areas and skills development are important considerations when taking forward information technology (IT) initiatives.

Benchmarking↗