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Biomedical subjects

B F Jaffe

Publications and source records attributed to B F Jaffe.

At least 19 recordsLinked to original sources

Are water and tympanotomy tubes compatible?

Traditionally, patients with tympanotomy tubes area admonished not to get water in ;their ears so that ear infections will not occur. This study reviews 100 children during the past three years who were given instructions to allow bath and shower water to get into their ears, and who were allowed to swim as long as they used polymyxin/neomycin/hydrocortisone ear drops at night after swimming. Only rarely did problems arise, and these were easily managed. No long-term harmful effects occurred. In addition, earplugs, swimming and shower caps, and special tympanotomy tubes are not needed to prevent ear infections. Water and tympanotomy tubes are compatible.

Baths

Recurrence of Wegener's granulomatosis after kidney transplantation. Successful re-induction of remission with cyclophosphamide.

A patient with Wegener's granulomatosis underwent successful kidney transplantation. After four years he had a recurrence of his disease while being maintained on azathiorpine. Substitution of cyclophosphamide for azathioprine resulted in a rapid remission of the Wegener's granulomatosis. Renal function has remained stable, and the patient has done well. As previous reports have suggested, it appears that cyclophosphamide is the immunosuppressive drug of choice in the treatment of Wegener's granulomatosis and that azathioprine is not as effective as cyclophosphamide in the treatment of this form of systemic vasculitis.

Adult

Viral causes of sudden inner ear deafness.

Clinical, pathologic, and laboratory studies suggesting a viral etiology for sudden deafness have been presented. Although a cause and effect relationship has not been proven, the frequent close association between viral infection and sudden deafness constitutes a strong argument in favor of a viral etiology of sudden deafness in about one of three patients with sudden deafness.

Acute Disease

Pinna anomalies associated with congenital conductive hearing loss.

This paper compares the normal pinna with the abnormal congenitally malformed pinna. Then the abnormal pinna is related to case histories where a hearing loss was found due to a congenital malformation of the middle ear ossicles. Careful examination of the pinna, therefore, may be a simple diagnostic sign of an underlying potentially surgically correctable hearing loss. An abnormal pinna is more often associated with a middle ear anomaly than with any other congenital malformation including a urinary tract anomaly.

Child