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Biomedical subjects

B Feiglin

Publications and source records attributed to B Feiglin.

5 recordsLinked to original sources
PubMed1979

The distribution of [14C] leucine and 85Sr labeled microspheres from rat incisor root canals.

The distribution of [14C] leucine and 85Sr labeled tracer microspheres from rat incisor pulp canals was investigated in an effort to establish the potential for passage of substances from within the root canal to the systemic circulation. Following introduction of the tracer materials into the pulp canals, the radioactivity in the lungs, spleen, kidney, liver, heart, blood, skeletal muscle, adrenal glands, salivary glands, and submandibular lymph nodes was determined. At all of the time intervals studied the incorporation of [14C] leucine into the adrenal gland was significantly greater than the [14C] leucine incorporation into the other organs. High levels of 85Sr labeled microspheres were detected in the ipsilateral submandibular glands and submandibular lymph nodes and in the lungs.

Animals↗
PubMed1979

Arteriovenous shunts demonstrated in the apical circulation of rat incisor teeth by the use of radio-labeled microspheres.

The distribution of systemically introduced 85Sr-labeled tracer microspheres to unexposed and previously exposed rat lower incisor tooth pulps was investigated. Fewer tracer microspheres entered the microcirculation of pulps that had been previously exposed as compared to control unexposed pulps. The presence of large numbers of dilated blood vessels in the apical tissues of teeth with exposed pulps was observed, and it is postulated that these vessels may be operating as arteriovenous anastomoses so that the pulpal microcirculation of teeth with inflamed pulps is bypassed by the tracer microspheres. The possible clinical significance of these findings is discussed.

Animals↗
PubMed1978

Protein and DNA levels in the submandibular salivary glands of isoproterenol stimulated mice.

The DNA and soluble and sedimental protein levels were studied in isoproterenol stimulated mouse submandibular salivary glands over a period of 200 h. Hypertrophy, the predominant cellular phenomenon following chronic isoproterenol treatment, was associated with a marked elevation of 14C-leucine incorporation into the buffer soluble protein fraction and a less pronounced isotope incorporation into the sedimental sub-cellular fraction as well as continued DNA synthesis. These findings are contrary to the accepted definitions of hypertrophy which preclude continued DNA synthesis. A suggestion is made, therefore, that in the system used the polyploidy associated with the hypertrophy involves.

Animals↗
PubMed1978

The pulp. A big issue about a little tissue.

Difficulties in correlating pulp symptomology with available histopathological and biochemical data have hampered understanding of pulp reaction to stimuli. Some of the less well known biochemical cell and tissue regulatory systems are appraised. Pathways whereby such systems could be implicated in pulp function are suggested.

Animals↗