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B Fernandes

Publications and source records attributed to B Fernandes.

66 records · Page 4Linked to original sources
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Analysis and function of T and B cell subpopulations in sarcoidosis.

Studies carried out in vitro with purified T cells from patients with sarcoidosis demonstrate that: 1. There is an important loss in peripheral blood T cells in active sarcoidosis. 2. These T cells seem to be functionally normal (PHA response, lymphokine production). 3. Memory cells to previously encountered antigens are still present in anergic sarcoidosis. 4. Stimulation of memory cells need the presence of sensitized macrophages from healthy individuals. 5. The stimulation of lymphokine producing T cells also need the presence of healthy macrophages. It is suggested that the development of anergy in sarcoidosis may result at least partly, from an abnormal function of macrophages.

B-Lymphocytes↗
PubMedDate not supplied

Antigen presenting cells and bone allotransplantation.

Antigen presenting cells may have a direct bearing on the results of allotransplantation of bone. There is no doubt that these cells are neither T nor B lymphocytes and that they do reside in the bone marrow. Evidence suggests that these bone marrow cells are of the granulocyte lineage and that they initiate immunologic reactions in vitro. The removal of bone marrow that contains these cells from bone allografts would decrease the immunologic response to the implantation of such transplants.

Animals↗