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Biomedical subjects

B Fierro

Publications and source records attributed to B Fierro.

At least 55 records · Page 3Linked to original sources
PubMed1983

[Hemorrheological survey in dystrophia myotonica and other muscular dystrophies].

We have determined the main hemorheological parameters in a group of patients suffering from myotonic dystrophy and in another group with oculopharyngeal or limb-girdle myopathy. From the results we have obtained it is evident that of all the rheological parameters considered only hematocrit, fibrinogen and fibrinogen/albumin ratio are different in patients with myotonic dystrophy when compared to that of normal controls. There were no variations in blood, plasma and serum viscosities and in erythrocyte filterability. In addition, hemorheological alterations were not present in patients with oculopharyngeal or limb-girdle myopathy.

Adult↗
PubMedDate not supplied

Prognostic value of somatosensory evoked potentials in stroke.

Median and tibial somatosensory evoked potentials (SEPs) were performed on 12 patients at three and twelve weeks after a first acute stroke, the relationship with motor and functional outcome as measured by British Medical Scale and Barthel Index was searched. Results indicated that the amplitude abnormalities of cortical potentials performed about three weeks after stroke are a good indicator of a poor motor and functional impairment after three months. Moreover changes in amplitude appeared more frequent and permanent than the latency abnormalities.

Aged↗
PubMedDate not supplied

Evoked potential study and radiological findings in patients with systemic lupus erythematosus.

We performed clinical, radiological (MRI) and neurophysiological (NCV, SEPs, and BAEPs) investigations in 36 unselected patients affected by Systemic Lupus Erythematosus (SLE). Fifteen patients (42%) presented clear neurological events and were considered as definite neuropsychiatric lupus (NPLE); 21 (58%) presented minor subjective complaints or no neurological problems referable to SLE and were considered as no-NPLE. Twenty-three patients (64%) showed neurophysiological abnormalities: 21 (58%) presented central abnormal neurophysiological measurements (including SEP and BAEP values), while 17 (47%) has slowed peripheral nerve conduction. Twenty-six out of 36 patients executed brain MRI examination. High intensity spots (HIS) in deep or subcortical white matter were the most common abnormalities and were present in 19 of the 26 patients (73%). We found that the incidence of neurophysiological and radiological abnormalities did not significantly differ in neurologically symptomatic and asymptomatic patients. Central nervous system impairment evidenced by abnormal N13-20 interpeak intervals (p = 0.05) and HIS (p = 0.01) findings was significantly associated with the presence of cutaneous vasculitis; while peripheral nerve involvement was significantly more frequent in patients with renal failure (p = 0.006).

Acute Kidney Injury↗
PubMedDate not supplied

P300 and respiratory findings in myotonic muscular dystrophy.

Ten patients with myotonic muscular dystrophy (MD) were examined by auditory event-related potentials (P300 ERPs), spirometric and blood gas analyses: arterial oxygen tension (PaO2), arterial carbon dioxide tension (PaCO2) and arterial oxygen saturation (SaO2). The aim of the study was to analyse the frequency of ERP abnormalities in this disease and to determine whether the neurophysiological evidence of cognitive impairment might be related to the ventilatory function abnormalities frequently described in MD. The mean P300 latency was significantly altered in MD patients compared with controls; P300 latencies did not correlate with spirometric parameters, blood gas values or with age, age at onset, duration or clinical status of the disease. This study provides neurophysiological evidence of cognitive impairment in MD patients. The cognitive deficits are not related to alveolar hypoventilation and appear to be a non progressive feature of the disease.

Adult↗
PubMedDate not supplied

[Velocity of nerve conduction in children and adolescents with type I diabetes mellitus: clinical, metabolic and immunologic correlations].

Clinical, metabolic, neurophysiologic and immunological data were obtained in a group of 50 patients with type I diabetes mellitus Results were compared with those obtained in 30 healthy subjects of comparable age. M.N.C. (median nerve conduction) velocities and sensitive latency were observed to be significant lower in the diabetic patients rather than in the controls. These abnormalities were correlated with the duration of diabetes rather than with the glucose control. The positivity for circulating immune complexes was found to be associated with a significant reduction of median sensory nerve conduction velocity. There results suggest that in addition to metabolic, genetic, vascular and hormonal abnormalities also immunologic factors may play a role in the pathogenesis of diabetic neuropathy.

Adolescent↗
PubMedDate not supplied

[Description of a case of multiple sclerosis with psychotic disorders at the onset].

The authors report on the case of a woman, aged 29, who was suffering for 15 years from an unipolar manic psychosis and for 5 years from ataxia, speech troubles and urine incontinence. The diagnosis of MS was supported by the presence of a marked increase of liquoral IgG as well as Link's and Tourtelotte's index. CT scan, EEG and VEPs were normal. The relationships between the two clinical conditions are briefly discussed on the view of data of the literature.

Adult↗